GO Annotations Graph

• Symbol: Dcaf1
• Name: DDB1 and CUL4 associated factor 1
• ID: MGI:2445220

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:1990244	histone H2AT120 kinase activity	ISO	J:164563
Molecular Function	GO:1990244	histone H2AT120 kinase activity	IBA	J:265628
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:164563
Molecular Function	GO:0030331	nuclear estrogen receptor binding	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72245
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	ISO	J:164563
Cellular Component	GO:0008180	COP9 signalosome	ISO	J:164563
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	ISO	J:164563
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0001650	fibrillar center	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0030183	B cell differentiation	IMP	J:181758
Biological Process	GO:0035212	cell competition in a multicellular organism	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0045732	positive regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0043687	post-translational protein modification	ISO	J:164563
Biological Process	GO:0016567	protein ubiquitination	IEA	J:72247
Biological Process	GO:0033151	V(D)J recombination	IMP	J:181758