GO Annotations Graph

• Symbol: Parp16
• Name: poly (ADP-ribose) polymerase family, member 16
• ID: MGI:2446133

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016757	glycosyltransferase activity	IEA	J:60000
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0019900	kinase binding	IBA	J:265628
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	IBA	J:265628
Molecular Function	GO:0140806	NAD+- protein-aspartate ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0140804	NAD+- protein-lysine ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	ISO	J:164563
Molecular Function	GO:0016779	nucleotidyltransferase activity	IEA	J:60000
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	ISO	J:164563
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	IBA	J:265628
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0045182	translation regulator activity	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	ISO	J:164563
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	IBA	J:265628
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	ISO	J:164563
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IBA	J:265628
Biological Process	GO:0036498	IRE1-mediated unfolded protein response	ISO	J:164563
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:2000766	negative regulation of cytoplasmic translation	ISO	J:164563
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0070213	protein auto-ADP-ribosylation	ISO	J:164563
Biological Process	GO:0006986	response to unfolded protein	IEA	J:60000