GO Annotations Graph

• Symbol: Fbxo2
• Name: F-box protein 2
• ID: MGI:2446216

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001540	amyloid-beta binding	IDA	J:39869
Molecular Function	GO:0030246	carbohydrate binding	IDA	J:86383
Molecular Function	GO:0031249	denatured protein binding	IDA	J:96950
Molecular Function	GO:0005515	protein binding	IPI	J:248223
Molecular Function	GO:0005515	protein binding	IPI	J:96950
Molecular Function	GO:0005515	protein binding	IPI	J:96950
Molecular Function	GO:0005515	protein binding	IPI	J:97815
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	IDA	J:163142
Cellular Component	GO:0005829	cytosol	TAS	J:96950
Cellular Component	GO:0043197	dendritic spine	IDA	J:97815
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0098890	extrinsic component of postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:97815
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:97815
Cellular Component	GO:0098978	glutamatergic synapse	IPI	J:97815
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:97815
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:97815
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0098794	postsynapse	IDA	J:97815
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	IDA	J:163142
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	IBA	J:265628
Biological Process	GO:0006516	glycoprotein catabolic process	IDA	J:163142
Biological Process	GO:0006516	glycoprotein catabolic process	IBA	J:265628
Biological Process	GO:0006516	glycoprotein catabolic process	IDA	J:96950
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0016567	protein ubiquitination	IDA	J:163142
Biological Process	GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	IDA	J:97815
Biological Process	GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	IMP	J:97815
Biological Process	GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	IPI	J:97815
Biological Process	GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	IDA	J:97815
Biological Process	GO:0099576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	IDA	J:97815
Biological Process	GO:0031396	regulation of protein ubiquitination	IDA	J:97815
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IDA	J:163142
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IBA	J:265628
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	IBA	J:265628
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	IDA	J:96950
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	IDA	J:96950