GO Annotations Graph

• Symbol: Setd1a
• Name: SET domain containing 1A
• ID: MGI:2446244

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:164563
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	TAS	J:185349
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IMP	J:263406
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	NAS	J:237693
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IMP	J:208420
Molecular Function	GO:0140945	histone H3K4 monomethyltransferase activity	IEA	J:72245
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:263406
Molecular Function	GO:0003723	RNA binding	IEA	J:72247
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000791	euchromatin	IDA	J:185349
Cellular Component	GO:0035097	histone methyltransferase complex	TAS	J:185349
Cellular Component	GO:0035097	histone methyltransferase complex	ISO	J:164563
Cellular Component	GO:0035097	histone methyltransferase complex	ISO	J:123598
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:208420
Cellular Component	GO:0005634	nucleus	ISO	J:123598
Cellular Component	GO:0005634	nucleus	IDA	J:208420
Cellular Component	GO:0048188	Set1C/COMPASS complex	TAS	J:237693
Cellular Component	GO:0048188	Set1C/COMPASS complex	ISO	J:164563
Cellular Component	GO:0048188	Set1C/COMPASS complex	IBA	J:265628
Biological Process	GO:0007420	brain development	IMP	J:296132
Biological Process	GO:0007420	brain development	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006974	DNA damage response	IEA	J:60000
Biological Process	GO:0051568	histone H3-K4 methylation	NAS	J:237693
Biological Process	GO:0051568	histone H3-K4 methylation	IBA	J:265628
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:237693
Biological Process	GO:2000179	positive regulation of neural precursor cell proliferation	IMP	J:208420
Biological Process	GO:2000648	positive regulation of stem cell proliferation	IMP	J:208420
Biological Process	GO:1902275	regulation of chromatin organization	ISO	J:164563
Biological Process	GO:1902275	regulation of chromatin organization	IDA	J:237693
Biological Process	GO:0045646	regulation of erythrocyte differentiation	IMP	J:237693
Biological Process	GO:1902036	regulation of hematopoietic stem cell differentiation	ISO	J:164563
Biological Process	GO:0019827	stem cell population maintenance	IMP	J:208420
Biological Process	GO:0072089	stem cell proliferation	IMP	J:208420
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	NAS	J:185349