GO Annotations Graph

• Symbol: Spire2
• Name: spire type actin nucleation factor 2
• ID: MGI:2446256

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0003779	actin binding	IEA	J:72247
Cellular Component	GO:0005938	cell cortex	IDA	J:180088
Cellular Component	GO:0005938	cell cortex	IBA	J:265628
Cellular Component	GO:0032154	cleavage furrow	IDA	J:174016
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	IDA	J:180088
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:174016
Biological Process	GO:0030036	actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0051639	actin filament network formation	IBA	J:265628
Biological Process	GO:0030041	actin filament polymerization	IBA	J:265628
Biological Process	GO:0045010	actin nucleation	IEA	J:72247
Biological Process	GO:0036089	cleavage furrow formation	IMP	J:174016
Biological Process	GO:0036089	cleavage furrow formation	IBA	J:265628
Biological Process	GO:0051295	establishment of meiotic spindle localization	ISO	J:164563
Biological Process	GO:0051295	establishment of meiotic spindle localization	IMP	J:174016
Biological Process	GO:0051295	establishment of meiotic spindle localization	IBA	J:265628
Biological Process	GO:0070649	formin-nucleated actin cable assembly	IMP	J:174016
Biological Process	GO:0070649	formin-nucleated actin cable assembly	ISO	J:164563
Biological Process	GO:0048193	Golgi vesicle transport	IBA	J:265628
Biological Process	GO:0046907	intracellular transport	IMP	J:180088
Biological Process	GO:0046907	intracellular transport	IBA	J:265628
Biological Process	GO:0040038	polar body extrusion after meiotic divisions	IMP	J:174016
Biological Process	GO:0040038	polar body extrusion after meiotic divisions	IBA	J:265628
Biological Process	GO:2000781	positive regulation of double-strand break repair	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0016192	vesicle-mediated transport	IMP	J:180088