GO Annotations Graph

• Symbol: Megf8
• Name: multiple EGF-like-domains 8
• ID: MGI:2446294

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Cellular Component	GO:0005634	nucleus	IDA	J:146805
Biological Process	GO:0030509	BMP signaling pathway	IGI	J:206541
Biological Process	GO:0042074	cell migration involved in gastrulation	ISO	J:164563
Biological Process	GO:0060976	coronary vasculature development	IMP	J:222159
Biological Process	GO:0097094	craniofacial suture morphogenesis	ISO	J:164563
Biological Process	GO:0071907	determination of digestive tract left/right asymmetry	IMP	J:146957
Biological Process	GO:0071907	determination of digestive tract left/right asymmetry	ISO	J:146805
Biological Process	GO:0061371	determination of heart left/right asymmetry	ISO	J:164563
Biological Process	GO:0061371	determination of heart left/right asymmetry	ISO	J:146805
Biological Process	GO:0061371	determination of heart left/right asymmetry	IMP	J:146957
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:222159
Biological Process	GO:0060971	embryonic heart tube left/right pattern formation	IMP	J:206541
Biological Process	GO:0003143	embryonic heart tube morphogenesis	IMP	J:206541
Biological Process	GO:0030326	embryonic limb morphogenesis	IMP	J:206541
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	IMP	J:206541
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	ISO	J:164563
Biological Process	GO:0097155	fasciculation of sensory neuron axon	IMP	J:206541
Biological Process	GO:0060972	left/right pattern formation	IMP	J:206541
Biological Process	GO:0060972	left/right pattern formation	ISO	J:164563
Biological Process	GO:0035108	limb morphogenesis	ISO	J:164563
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	IMP	J:253667
Biological Process	GO:1900164	nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	ISO	J:146805
Biological Process	GO:0048842	positive regulation of axon extension involved in axon guidance	IMP	J:206541
Biological Process	GO:0010468	regulation of gene expression	IMP	J:206541