GO Annotations Graph

• Symbol: Dennd1b
• Name: DENN domain containing 1B
• ID: MGI:2447812

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IMP	J:229307
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	ISO	J:164563
Molecular Function	GO:1901981	phosphatidylinositol phosphate binding	IBA	J:265628
Molecular Function	GO:0031267	small GTPase binding	IPI	J:229307
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	IBA	J:265628
Biological Process	GO:0032456	endocytic recycling	IMP	J:229307
Biological Process	GO:0032456	endocytic recycling	IBA	J:265628
Biological Process	GO:0006897	endocytosis	IBA	J:265628
Biological Process	GO:0043547	positive regulation of GTPase activity	IMP	J:229307
Biological Process	GO:2000553	positive regulation of T-helper 2 cell cytokine production	IMP	J:229307
Biological Process	GO:2000553	positive regulation of T-helper 2 cell cytokine production	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0050776	regulation of immune response	IMP	J:229307
Biological Process	GO:0050852	T cell receptor signaling pathway	IMP	J:229307
Biological Process	GO:0050852	T cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050852	T cell receptor signaling pathway	IBA	J:265628