GO Annotations Graph

• Symbol: Pip4p1
• Name: phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
• ID: MGI:2448501

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	ISO	J:164563
Molecular Function	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:274778
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0031902	late endosome membrane	IDA	J:283186
Cellular Component	GO:0031902	late endosome membrane	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	IBA	J:265628
Cellular Component	GO:0005765	lysosomal membrane	IDA	J:274778
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	IBA	J:265628
Cellular Component	GO:0005764	lysosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0030670	phagocytic vesicle membrane	IDA	J:283186
Cellular Component	GO:0030670	phagocytic vesicle membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:283186
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0008203	cholesterol metabolic process	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0032418	lysosome localization	ISO	J:164563
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	ISO	J:164563
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	IBA	J:265628
Biological Process	GO:1904263	positive regulation of TORC1 signaling	ISO	J:164563
Biological Process	GO:1904263	positive regulation of TORC1 signaling	IMP	J:274778
Biological Process	GO:0070070	proton-transporting V-type ATPase complex assembly	IMP	J:274778
Biological Process	GO:0006991	response to sterol depletion	ISO	J:164563