GO Annotations Graph

• Symbol: Nr1d2
• Name: nuclear receptor subfamily 1, group D, member 2
• ID: MGI:2449205

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:203405
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	IDA	J:203378
Molecular Function	GO:0003677	DNA binding	IDA	J:20436
Molecular Function	GO:0003677	DNA binding	IDA	J:23754
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:20436
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:23754
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:242552
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:182418
Molecular Function	GO:0005515	protein binding	IPI	J:218799
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:242552
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IEA	J:72247
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	IDA	J:273537
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:273537
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0048512	circadian behavior	IMP	J:265505
Biological Process	GO:0097009	energy homeostasis	IMP	J:203407
Biological Process	GO:0009755	hormone-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0055088	lipid homeostasis	IMP	J:203407
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:203378
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:203405
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:203407
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:265505
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0050728	negative regulation of inflammatory response	IMP	J:264705
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:242552
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:203405
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0042752	regulation of circadian rhythm	IDA	J:203378
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:264705
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:23754
Biological Process	GO:0050727	regulation of inflammatory response	IMP	J:203407
Biological Process	GO:0019216	regulation of lipid metabolic process	IMP	J:203407
Biological Process	GO:2001014	regulation of skeletal muscle cell differentiation	IMP	J:203407
Biological Process	GO:0048511	rhythmic process	IEA	J:60000