GO Annotations Graph

• Symbol: Gba2
• Name: glucosidase beta 2
• ID: MGI:2654325

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008422	beta-glucosidase activity	ISO	J:164563
Molecular Function	GO:0008422	beta-glucosidase activity	IBA	J:265628
Molecular Function	GO:0008422	beta-glucosidase activity	IDA	J:286765
Molecular Function	GO:0008422	beta-glucosidase activity	IMP	J:286765
Molecular Function	GO:0004336	galactosylceramidase activity	IEA	J:72245
Molecular Function	GO:0004348	glucosylceramidase activity	IDA	J:195545
Molecular Function	GO:0004348	glucosylceramidase activity	IDA	J:114991
Molecular Function	GO:0004348	glucosylceramidase activity	ISO	J:164563
Molecular Function	GO:0004348	glucosylceramidase activity	IMP	J:286765
Molecular Function	GO:0004348	glucosylceramidase activity	IDA	J:286765
Molecular Function	GO:0046527	glucosyltransferase activity	IDA	J:114991
Molecular Function	GO:0046527	glucosyltransferase activity	IDA	J:231478
Molecular Function	GO:0016757	glycosyltransferase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016798	hydrolase activity, acting on glycosyl bonds	IEA	J:60000
Molecular Function	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEA	J:72247
Molecular Function	GO:0050295	steryl-beta-glucosidase activity	IDA	J:231478
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:195545
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0042406	extrinsic component of endoplasmic reticulum membrane	IDA	J:195545
Cellular Component	GO:0090498	extrinsic component of Golgi membrane	IDA	J:195545
Cellular Component	GO:0019898	extrinsic component of membrane	IDA	J:195545
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:164563
Biological Process	GO:0005975	carbohydrate metabolic process	IEA	J:72247
Biological Process	GO:0007417	central nervous system development	IBA	J:265628
Biological Process	GO:0021954	central nervous system neuron development	ISO	J:164563
Biological Process	GO:0008203	cholesterol metabolic process	IMP	J:231478
Biological Process	GO:0006680	glucosylceramide catabolic process	ISO	J:164563
Biological Process	GO:0006680	glucosylceramide catabolic process	IDA	J:195545
Biological Process	GO:0006680	glucosylceramide catabolic process	IMP	J:114991
Biological Process	GO:0016139	glycoside catabolic process	ISO	J:164563
Biological Process	GO:0030259	lipid glycosylation	IDA	J:231478
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0030833	regulation of actin filament polymerization	IMP	J:224223
Biological Process	GO:0097035	regulation of membrane lipid distribution	IMP	J:224223
Biological Process	GO:0031113	regulation of microtubule polymerization	IMP	J:224223
Biological Process	GO:0006665	sphingolipid metabolic process	IEA	J:60000
Biological Process	GO:0008202	steroid metabolic process	IEA	J:60000