GO Annotations Graph

• Symbol: Grhl3
• Name: grainyhead like transcription factor 3
• ID: MGI:2655333

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:162624
Molecular Function	GO:0005515	protein binding	IPI	J:114626
Molecular Function	GO:0005515	protein binding	IPI	J:82770
Molecular Function	GO:0005515	protein binding	IPI	J:82770
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:97429
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:82770
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:168020
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:82770
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:82770
Biological Process	GO:0007417	central nervous system development	IMP	J:73993
Biological Process	GO:0090103	cochlea morphogenesis	IGI	J:162624
Biological Process	GO:0007398	ectoderm development	IMP	J:86772
Biological Process	GO:0008544	epidermis development	IMP	J:168020
Biological Process	GO:0008544	epidermis development	IMP	J:114626
Biological Process	GO:0008544	epidermis development	IMP	J:97429
Biological Process	GO:0001736	establishment of planar polarity	IGI	J:162624
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:218401
Biological Process	GO:0061029	eyelid development in camera-type eye	IMP	J:170759
Biological Process	GO:0010467	gene expression	IMP	J:235073
Biological Process	GO:0001843	neural tube closure	IMP	J:114626
Biological Process	GO:0001843	neural tube closure	IMP	J:164805
Biological Process	GO:0007389	pattern specification process	IMP	J:86772
Biological Process	GO:0090179	planar cell polarity pathway involved in neural tube closure	IGI	J:162624
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:82770
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:150849
Biological Process	GO:0043547	positive regulation of GTPase activity	IGI	J:162624
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:162624
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	ISO	J:73065
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006366	transcription by RNA polymerase II	IMP	J:162624
Biological Process	GO:0042060	wound healing	IGI	J:162624
Biological Process	GO:0042060	wound healing	IGI	J:162624
Biological Process	GO:0042060	wound healing	IMP	J:97429
Biological Process	GO:0042060	wound healing	IGI	J:162624
Biological Process	GO:0042060	wound healing	IGI	J:162624