GO Annotations Graph

• Symbol: Dtx3l
• Name: deltex 3-like, E3 ubiquitin ligase
• ID: MGI:2656973

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0004857	enzyme inhibitor activity	ISO	J:164563
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0140852	histone ubiquitin ligase activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0140768	protein ADP-ribosyltransferase-substrate adaptor activity	ISO	J:164563
Molecular Function	GO:0097677	STAT family protein binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0044389	ubiquitin-like protein ligase binding	ISO	J:164563
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0051607	defense response to virus	IEA	J:60000
Biological Process	GO:0000077	DNA damage checkpoint signaling	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:0006302	double-strand break repair	ISO	J:164563
Biological Process	GO:0008333	endosome to lysosome transport	ISO	J:164563
Biological Process	GO:0010390	histone monoubiquitination	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:0051444	negative regulation of ubiquitin-protein transferase activity	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	IEA	J:72247
Biological Process	GO:0035563	positive regulation of chromatin binding	ISO	J:164563
Biological Process	GO:0002230	positive regulation of defense response to virus by host	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:164563
Biological Process	GO:1902966	positive regulation of protein localization to early endosome	ISO	J:164563
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	ISO	J:164563
Biological Process	GO:2000646	positive regulation of receptor catabolic process	ISO	J:164563
Biological Process	GO:0051865	protein autoubiquitination	ISO	J:164563
Biological Process	GO:0070936	protein K48-linked ubiquitination	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0016567	protein ubiquitination	IEA	J:72247
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	ISO	J:164563