GO Annotations Graph

• Symbol: Neu4
• Name: sialidase 4
• ID: MGI:2661364

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	IDA	J:153180
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	ISO	J:164563
Molecular Function	GO:0052795	exo-alpha-(2->6)-sialidase activity	IEA	J:72245
Molecular Function	GO:0052796	exo-alpha-(2->8)-sialidase activity	IDA	J:185058
Molecular Function	GO:0052796	exo-alpha-(2->8)-sialidase activity	IDA	J:153180
Molecular Function	GO:0052796	exo-alpha-(2->8)-sialidase activity	ISO	J:164563
Molecular Function	GO:0004308	exo-alpha-sialidase activity	ISO	J:164563
Molecular Function	GO:0004308	exo-alpha-sialidase activity	IBA	J:265628
Molecular Function	GO:0004308	exo-alpha-sialidase activity	IDA	J:86819
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0016798	hydrolase activity, acting on glycosyl bonds	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IEA	J:60000
Cellular Component	GO:0005764	lysosome	IBA	J:265628
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0043005	neuron projection	IDA	J:185058
Cellular Component	GO:0019866	organelle inner membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:185058
Biological Process	GO:0005975	carbohydrate metabolic process	IEA	J:60000
Biological Process	GO:0006689	ganglioside catabolic process	IDA	J:153180
Biological Process	GO:0006689	ganglioside catabolic process	ISO	J:164563
Biological Process	GO:0006689	ganglioside catabolic process	IBA	J:265628
Biological Process	GO:0006516	glycoprotein catabolic process	IDA	J:185058
Biological Process	GO:0006516	glycoprotein catabolic process	ISO	J:164563
Biological Process	GO:0006516	glycoprotein catabolic process	IDA	J:153180
Biological Process	GO:0016042	lipid catabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0010977	negative regulation of neuron projection development	IDA	J:185058
Biological Process	GO:0009313	oligosaccharide catabolic process	ISO	J:164563
Biological Process	GO:0009313	oligosaccharide catabolic process	IBA	J:265628