GO Annotations Graph

• Symbol: Adap2
• Name: ArfGAP with dual PH domains 2
• ID: MGI:2663075

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005545	1-phosphatidylinositol binding	ISO	J:155856
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:1902936	phosphatidylinositol bisphosphate binding	IEA	J:72247
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ISO	J:155856
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	IBA	J:265628
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ISO	J:73065
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	ISO	J:155856
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005740	mitochondrial envelope	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:73065
Biological Process	GO:0007507	heart development	NAS	J:114730
Biological Process	GO:0007507	heart development	IBA	J:265628
Biological Process	GO:0048017	inositol lipid-mediated signaling	ISO	J:73065
Biological Process	GO:0043547	positive regulation of GTPase activity	IEA	J:72247
Biological Process	GO:0043087	regulation of GTPase activity	IBA	J:265628