GO Annotations Graph

• Symbol: Wfikkn2
• Name: WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
• ID: MGI:2669209

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004857	enzyme inhibitor activity	IEA	J:60000
Molecular Function	GO:0008191	metalloendopeptidase inhibitor activity	IEA	J:60000
Molecular Function	GO:0030414	peptidase inhibitor activity	IEA	J:60000
Molecular Function	GO:0030414	peptidase inhibitor activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:85741
Molecular Function	GO:0005515	protein binding	IPI	J:201148
Molecular Function	GO:0048019	receptor antagonist activity	ISO	J:164563
Molecular Function	GO:0048019	receptor antagonist activity	IBA	J:265628
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	IEA	J:72247
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	IEA	J:60000
Molecular Function	GO:0050431	transforming growth factor beta binding	ISO	J:164563
Molecular Function	GO:0050431	transforming growth factor beta binding	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IDA	J:201148
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IDA	J:85741
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Biological Process	GO:0055001	muscle cell development	IMP	J:201148
Biological Process	GO:0043392	negative regulation of DNA binding	IDA	J:201148
Biological Process	GO:0010466	negative regulation of peptidase activity	IEA	J:60000
Biological Process	GO:0032091	negative regulation of protein binding	IDA	J:201148
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0060021	roof of mouth development	IGI	J:201148
Biological Process	GO:0001501	skeletal system development	IGI	J:201148
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IDA	J:85741