GO Annotations Graph

• Symbol: Crb3
• Name: crumbs family member 3
• ID: MGI:2670904

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0017124	SH3 domain binding	ISO	J:164563
Cellular Component	GO:0045177	apical part of cell	IDA	J:202984
Cellular Component	GO:0016324	apical plasma membrane	ISA	J:84636
Cellular Component	GO:0005923	bicellular tight junction	IEA	J:60000
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0035003	subapical complex	IDA	J:114927
Biological Process	GO:0045216	cell-cell junction organization	ISA	J:84636
Biological Process	GO:0045198	establishment of epithelial cell apical/basal polarity	ISA	J:84636
Biological Process	GO:1901890	positive regulation of cell junction assembly	IMP	J:169049
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563