GO Annotations Graph

• Symbol: Tnfsf18
• Name: tumor necrosis factor (ligand) superfamily, member 18
• ID: MGI:2673064

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005125	cytokine activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:131097
Molecular Function	GO:0042802	identical protein binding	IPI	J:131029
Molecular Function	GO:0005515	protein binding	IPI	J:131097
Molecular Function	GO:0005515	protein binding	IPI	J:114773
Molecular Function	GO:0032813	tumor necrosis factor receptor superfamily binding	IDA	J:180483
Molecular Function	GO:0032813	tumor necrosis factor receptor superfamily binding	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:180483
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:2000329	negative regulation of T-helper 17 cell lineage commitment	IMP	J:206613
Biological Process	GO:0045785	positive regulation of cell adhesion	IMP	J:220504
Biological Process	GO:0045785	positive regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0050729	positive regulation of inflammatory response	IMP	J:206613
Biological Process	GO:0002687	positive regulation of leukocyte migration	ISO	J:164563
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	IMP	J:206613
Biological Process	GO:0090026	positive regulation of monocyte chemotaxis	IMP	J:206613
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IMP	J:180483
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	ISO	J:164563
Biological Process	GO:2000508	regulation of dendritic cell chemotaxis	IMP	J:206613
Biological Process	GO:0043254	regulation of protein-containing complex assembly	IMP	J:206613
Biological Process	GO:0042129	regulation of T cell proliferation	IDA	J:86980
Biological Process	GO:0042129	regulation of T cell proliferation	IBA	J:265628
Biological Process	GO:0002309	T cell proliferation involved in immune response	IDA	J:86980
Biological Process	GO:0002309	T cell proliferation involved in immune response	IBA	J:265628
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	IMP	J:180483
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	IBA	J:265628