GO Annotations Graph

• Symbol: P2ry6
• Name: pyrimidinergic receptor P2Y, G-protein coupled, 6
• ID: MGI:2673874

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001621	G protein-coupled ADP receptor activity	ISO	J:164563
Molecular Function	GO:0001621	G protein-coupled ADP receptor activity	IBA	J:265628
Molecular Function	GO:0045028	G protein-coupled purinergic nucleotide receptor activity	IEA	J:72247
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:72247
Molecular Function	GO:0045029	G protein-coupled UDP receptor activity	ISO	J:164563
Molecular Function	GO:0045029	G protein-coupled UDP receptor activity	IBA	J:265628
Molecular Function	GO:0045029	G protein-coupled UDP receptor activity	IDA	J:85117
Molecular Function	GO:0045030	G protein-coupled UTP receptor activity	ISO	J:164563
Molecular Function	GO:0045030	G protein-coupled UTP receptor activity	IBA	J:265628
Molecular Function	GO:0019103	pyrimidine nucleotide binding	IC	J:85117
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0071407	cellular response to organic cyclic compound	IDA	J:194901
Biological Process	GO:0071380	cellular response to prostaglandin E stimulus	IDA	J:194901
Biological Process	GO:0071415	cellular response to purine-containing compound	ISO	J:164563
Biological Process	GO:1905835	cellular response to pyrimidine ribonucleotide	ISO	J:155856
Biological Process	GO:1905835	cellular response to pyrimidine ribonucleotide	ISO	J:164563
Biological Process	GO:1905835	cellular response to pyrimidine ribonucleotide	IBA	J:265628
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0006909	phagocytosis	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	ISO	J:155856
Biological Process	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	ISO	J:164563
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	ISO	J:155856
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0030321	transepithelial chloride transport	IDA	J:85117