GO Annotations Graph

• Symbol: Tnfrsf14
• Name: tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
• ID: MGI:2675303

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019955	cytokine binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:94873
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0001618	virus receptor activity	IEA	J:60000
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:94873
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-6790089
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	IDA	J:94873
Biological Process	GO:0002367	cytokine production involved in immune response	IMP	J:168073
Biological Process	GO:0050829	defense response to Gram-negative bacterium	IBA	J:265628
Biological Process	GO:0050829	defense response to Gram-negative bacterium	IMP	J:186687
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IBA	J:265628
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:186687
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IEA	J:60000
Biological Process	GO:1905675	negative regulation of adaptive immune memory response	ISO	J:164563
Biological Process	GO:0046642	negative regulation of alpha-beta T cell proliferation	IBA	J:265628
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	IDA	J:94873
Biological Process	GO:0002720	positive regulation of cytokine production involved in immune response	IBA	J:265628
Biological Process	GO:0002720	positive regulation of cytokine production involved in immune response	IMP	J:168073
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IBA	J:265628
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA	J:94873
Biological Process	GO:2000406	positive regulation of T cell migration	IBA	J:265628
Biological Process	GO:2000406	positive regulation of T cell migration	IMP	J:168073
Biological Process	GO:0031295	T cell costimulation	ISO	J:164563
Biological Process	GO:0072678	T cell migration	IMP	J:168073