GO Annotations Graph

• Symbol: Nlgn2
• Name: neuroligin 2
• ID: MGI:2681835

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	IPI	J:175310
Molecular Function	GO:0042802	identical protein binding	IPI	J:248265
Molecular Function	GO:0042043	neurexin family protein binding	IPI	J:175310
Molecular Function	GO:0042043	neurexin family protein binding	IPI	J:175310
Molecular Function	GO:0042043	neurexin family protein binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:265620
Molecular Function	GO:0005515	protein binding	IPI	J:200384
Molecular Function	GO:0005515	protein binding	IPI	J:256117
Molecular Function	GO:0005515	protein binding	IPI	J:256117
Molecular Function	GO:0005515	protein binding	IPI	J:256117
Molecular Function	GO:0038023	signaling receptor activity	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:256117
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0098691	dopaminergic synapse	IDA	J:232120
Cellular Component	GO:0098691	dopaminergic synapse	IDA	J:232120
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	IC	J:175189
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:256117
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:175189
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:175189
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:175189
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:175189
Cellular Component	GO:0098690	glycinergic synapse	IDA	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IPI	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IDA	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IPI	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IMP	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IMP	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IDA	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IPI	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IDA	J:154925
Cellular Component	GO:0060077	inhibitory synapse	IC	J:175189
Cellular Component	GO:0060077	inhibitory synapse	IC	J:138036
Cellular Component	GO:0060077	inhibitory synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0099634	postsynaptic specialization membrane	IDA	J:232120
Cellular Component	GO:0099634	postsynaptic specialization membrane	IDA	J:232120
Cellular Component	GO:0097470	ribbon synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0045202	synapse	IDA	J:96464
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0097116	gephyrin clustering involved in postsynaptic density assembly	IDA	J:175189
Biological Process	GO:0097116	gephyrin clustering involved in postsynaptic density assembly	IMP	J:256117
Biological Process	GO:0097116	gephyrin clustering involved in postsynaptic density assembly	IGI	J:256117
Biological Process	GO:0097116	gephyrin clustering involved in postsynaptic density assembly	IMP	J:256117
Biological Process	GO:1904862	inhibitory synapse assembly	IDA	J:232984
Biological Process	GO:1901142	insulin metabolic process	ISO	J:155856
Biological Process	GO:0007630	jump response	ISO	J:155856
Biological Process	GO:0035641	locomotory exploration behavior	IMP	J:151145
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IGI	J:113647
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:151145
Biological Process	GO:0007158	neuron cell-cell adhesion	ISO	J:155856
Biological Process	GO:0007158	neuron cell-cell adhesion	IBA	J:265628
Biological Process	GO:0072578	neurotransmitter-gated ion channel clustering	IGI	J:256117
Biological Process	GO:0072578	neurotransmitter-gated ion channel clustering	IMP	J:256117
Biological Process	GO:0072578	neurotransmitter-gated ion channel clustering	IDA	J:256117
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IMP	J:175189
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	IMP	J:175189
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	ISO	J:155856
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	IMP	J:138036
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:155856
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:164563
Biological Process	GO:1902474	positive regulation of protein localization to synapse	ISO	J:155856
Biological Process	GO:1902474	positive regulation of protein localization to synapse	ISO	J:211830
Biological Process	GO:0051965	positive regulation of synapse assembly	ISO	J:155856
Biological Process	GO:0032230	positive regulation of synaptic transmission, GABAergic	IMP	J:175189
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	IMP	J:175189
Biological Process	GO:2000809	positive regulation of synaptic vesicle clustering	IDA	J:175189
Biological Process	GO:1904034	positive regulation of t-SNARE clustering	ISO	J:155856
Biological Process	GO:0097119	postsynaptic density protein 95 clustering	IDA	J:175189
Biological Process	GO:0097104	postsynaptic membrane assembly	IDA	J:175189
Biological Process	GO:0097104	postsynaptic membrane assembly	IBA	J:265628
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:175189
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:175189
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:175189
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:175189
Biological Process	GO:0097105	presynaptic membrane assembly	IMP	J:151145
Biological Process	GO:0097105	presynaptic membrane assembly	ISO	J:155856
Biological Process	GO:0097105	presynaptic membrane assembly	IDA	J:175189
Biological Process	GO:0097105	presynaptic membrane assembly	IBA	J:265628
Biological Process	GO:0034394	protein localization to cell surface	IMP	J:256117
Biological Process	GO:0034394	protein localization to cell surface	IMP	J:256117
Biological Process	GO:0034394	protein localization to cell surface	IDA	J:256117
Biological Process	GO:0035418	protein localization to synapse	IDA	J:175189
Biological Process	GO:0035418	protein localization to synapse	IDA	J:232984
Biological Process	GO:2000311	regulation of AMPA receptor activity	IMP	J:175189
Biological Process	GO:1905606	regulation of presynapse assembly	ISO	J:155856
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	IGI	J:113647
Biological Process	GO:0019233	sensory perception of pain	IMP	J:151145
Biological Process	GO:0035176	social behavior	ISO	J:155856
Biological Process	GO:0007416	synapse assembly	ISO	J:155856
Biological Process	GO:0050808	synapse organization	ISO	J:96464
Biological Process	GO:0050808	synapse organization	ISO	J:73065
Biological Process	GO:0051932	synaptic transmission, GABAergic	IGI	J:256117
Biological Process	GO:0051932	synaptic transmission, GABAergic	IMP	J:256117
Biological Process	GO:0051932	synaptic transmission, GABAergic	IMP	J:256117
Biological Process	GO:0051932	synaptic transmission, GABAergic	IDA	J:256117
Biological Process	GO:0048488	synaptic vesicle endocytosis	IBA	J:265628
Biological Process	GO:0072553	terminal button organization	ISO	J:155856
Biological Process	GO:0001966	thigmotaxis	ISO	J:155856