Nlgn2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nlgn2
neuroligin 2
MGI:2681835

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	IPI	J:175310
Molecular Function	GO:0042802	identical protein binding	IPI	J:248265
Molecular Function	GO:0042043	neurexin family protein binding	IPI	J:175310
Molecular Function	GO:0042043	neurexin family protein binding	IPI	J:175310
Molecular Function	GO:0042043	neurexin family protein binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:265620
Molecular Function	GO:0005515	protein binding	IPI	J:200384
Molecular Function	GO:0005515	protein binding	IPI	J:256117
Molecular Function	GO:0005515	protein binding	IPI	J:256117
Molecular Function	GO:0005515	protein binding	IPI	J:256117
Molecular Function	GO:0038023	signaling receptor activity	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:256117
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0043198	dendritic shaft	ISO	J:155856
Cellular Component	GO:0098691	dopaminergic synapse	IDA	J:232120
Cellular Component	GO:0098691	dopaminergic synapse	IDA	J:232120
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0060076	excitatory synapse	IC	J:175189
Cellular Component	GO:0098982	GABA-ergic synapse	ISO	J:155856
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:256117
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IPI	J:154925
Cellular Component	GO:0098982	GABA-ergic synapse	IMP	J:175189
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:175189
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:175189
Cellular Component	GO:0098982	GABA-ergic synapse	IDA	J:175189
Cellular Component	GO:0098690	glycinergic synapse	IDA	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IPI	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IDA	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IPI	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IMP	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IMP	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IDA	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IPI	J:154925
Cellular Component	GO:0098690	glycinergic synapse	IDA	J:154925
Cellular Component	GO:0060077	inhibitory synapse	IC	J:175189
Cellular Component	GO:0060077	inhibitory synapse	IC	J:138036
Cellular Component	GO:0060077	inhibitory synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0099634	postsynaptic specialization membrane	ISO	J:155856
Cellular Component	GO:0099634	postsynaptic specialization membrane	IDA	J:232120
Cellular Component	GO:0099634	postsynaptic specialization membrane	IDA	J:232120
Cellular Component	GO:0097470	ribbon synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	IBA	J:265628
Cellular Component	GO:0045202	synapse	IDA	J:96464
Biological Process	GO:0007155	cell adhesion	IEA	J:72247
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0097116	gephyrin clustering involved in postsynaptic density assembly	IDA	J:175189
Biological Process	GO:0097116	gephyrin clustering involved in postsynaptic density assembly	IMP	J:256117
Biological Process	GO:0097116	gephyrin clustering involved in postsynaptic density assembly	IGI	J:256117
Biological Process	GO:0097116	gephyrin clustering involved in postsynaptic density assembly	IMP	J:256117
Biological Process	GO:1904862	inhibitory synapse assembly	IDA	J:232984
Biological Process	GO:1901142	insulin metabolic process	ISO	J:155856
Biological Process	GO:0007630	jump response	ISO	J:155856
Biological Process	GO:0035641	locomotory exploration behavior	IMP	J:151145
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IGI	J:113647
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:151145
Biological Process	GO:0007158	neuron cell-cell adhesion	ISO	J:155856
Biological Process	GO:0007158	neuron cell-cell adhesion	IBA	J:265628
Biological Process	GO:0072578	neurotransmitter-gated ion channel clustering	IGI	J:256117
Biological Process	GO:0072578	neurotransmitter-gated ion channel clustering	IMP	J:256117
Biological Process	GO:0072578	neurotransmitter-gated ion channel clustering	IDA	J:256117
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IMP	J:175189
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	IMP	J:175189
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	ISO	J:155856
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	IMP	J:138036
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:155856
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:164563
Biological Process	GO:1902474	positive regulation of protein localization to synapse	ISO	J:155856
Biological Process	GO:1902474	positive regulation of protein localization to synapse	ISO	J:211830
Biological Process	GO:0051965	positive regulation of synapse assembly	ISO	J:155856
Biological Process	GO:0032230	positive regulation of synaptic transmission, GABAergic	IMP	J:175189
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	IMP	J:175189
Biological Process	GO:2000809	positive regulation of synaptic vesicle clustering	IDA	J:175189
Biological Process	GO:1904034	positive regulation of t-SNARE clustering	ISO	J:155856
Biological Process	GO:0097119	postsynaptic density protein 95 clustering	IDA	J:175189
Biological Process	GO:0097104	postsynaptic membrane assembly	IDA	J:175189
Biological Process	GO:0097104	postsynaptic membrane assembly	IBA	J:265628
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IPI	J:154925
Biological Process	GO:0098698	postsynaptic specialization assembly	IMP	J:175189
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:175189
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:175189
Biological Process	GO:0098698	postsynaptic specialization assembly	IDA	J:175189
Biological Process	GO:0097105	presynaptic membrane assembly	IMP	J:151145
Biological Process	GO:0097105	presynaptic membrane assembly	ISO	J:155856
Biological Process	GO:0097105	presynaptic membrane assembly	IDA	J:175189
Biological Process	GO:0097105	presynaptic membrane assembly	IBA	J:265628
Biological Process	GO:0034394	protein localization to cell surface	IMP	J:256117
Biological Process	GO:0034394	protein localization to cell surface	IMP	J:256117
Biological Process	GO:0034394	protein localization to cell surface	IDA	J:256117
Biological Process	GO:0035418	protein localization to synapse	IDA	J:175189
Biological Process	GO:0035418	protein localization to synapse	IDA	J:232984
Biological Process	GO:2000311	regulation of AMPA receptor activity	IMP	J:175189
Biological Process	GO:1905606	regulation of presynapse assembly	ISO	J:155856
Biological Process	GO:0002087	regulation of respiratory gaseous exchange by nervous system process	IGI	J:113647
Biological Process	GO:0019233	sensory perception of pain	IMP	J:151145
Biological Process	GO:0035176	social behavior	ISO	J:155856
Biological Process	GO:0007416	synapse assembly	ISO	J:155856
Biological Process	GO:0050808	synapse organization	ISO	J:96464
Biological Process	GO:0050808	synapse organization	ISO	J:73065
Biological Process	GO:0051932	synaptic transmission, GABAergic	IGI	J:256117
Biological Process	GO:0051932	synaptic transmission, GABAergic	IMP	J:256117
Biological Process	GO:0051932	synaptic transmission, GABAergic	IMP	J:256117
Biological Process	GO:0051932	synaptic transmission, GABAergic	IDA	J:256117
Biological Process	GO:0048488	synaptic vesicle endocytosis	IBA	J:265628
Biological Process	GO:0072553	terminal button organization	ISO	J:155856
Biological Process	GO:0001966	thigmotaxis	ISO	J:155856

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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