GO Annotations Graph

• Symbol: Obscn
• Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
• ID: MGI:2681862

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030506	ankyrin binding	ISO	J:164563
Molecular Function	GO:0030506	ankyrin binding	ISO	J:73065
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0045296	cadherin binding	IPI	J:197851
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	IEA	J:72247
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0008289	lipid binding	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:1902936	phosphatidylinositol bisphosphate binding	IDA	J:281255
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	ISO	J:164563
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	ISO	J:164563
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	ISO	J:164563
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	ISO	J:164563
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:197851
Molecular Function	GO:0004672	protein kinase activity	IDA	J:197851
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:72245
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0008307	structural constituent of muscle	IEA	J:72247
Molecular Function	GO:0031432	titin binding	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IDA	J:197851
Cellular Component	GO:0014704	intercalated disc	IDA	J:197851
Cellular Component	GO:0031430	M band	IDA	J:197851
Cellular Component	GO:0031430	M band	IDA	J:143121
Cellular Component	GO:0031430	M band	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:281255
Cellular Component	GO:0042383	sarcolemma	IDA	J:197851
Cellular Component	GO:0030017	sarcomere	ISO	J:155856
Cellular Component	GO:0005863	striated muscle myosin thick filament	ISO	J:73065
Cellular Component	GO:0030018	Z disc	IDA	J:197851
Cellular Component	GO:0030018	Z disc	ISO	J:155856
Cellular Component	GO:0030018	Z disc	ISO	J:73065
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	IDA	J:281255
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:197851
Biological Process	GO:0006468	protein phosphorylation	IDA	J:197851