GO Annotations Graph

• Symbol: Asxl1
• Name: ASXL transcriptional regulator 1
• ID: MGI:2684063

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	IDA	J:114350
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	IDA	J:183204
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:114350
Molecular Function	GO:0005515	protein binding	IPI	J:187380
Molecular Function	GO:0005515	protein binding	IPI	J:204177
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:114350
Cellular Component	GO:0005634	nucleus	IDA	J:204177
Cellular Component	GO:0035517	PR-DUB complex	ISO	J:164563
Cellular Component	GO:0035517	PR-DUB complex	IBA	J:265628
Biological Process	GO:0009887	animal organ morphogenesis	IBA	J:265628
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:155898
Biological Process	GO:0060348	bone development	IMP	J:188142
Biological Process	GO:0048539	bone marrow development	IMP	J:155898
Biological Process	GO:0000902	cell morphogenesis	IMP	J:155898
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0003007	heart morphogenesis	IMP	J:213577
Biological Process	GO:0048534	hematopoietic or lymphoid organ development	IMP	J:155898
Biological Process	GO:0030097	hemopoiesis	IMP	J:155898
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:155898
Biological Process	GO:0060430	lung saccule development	IMP	J:213577
Biological Process	GO:0035522	monoubiquitinated histone H2A deubiquitination	ISO	J:164563
Biological Process	GO:0045599	negative regulation of fat cell differentiation	IDA	J:183204
Biological Process	GO:0010888	negative regulation of lipid storage	ISO	J:155856
Biological Process	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway	IDA	J:183204
Biological Process	GO:0072015	podocyte development	IMP	J:229413
Biological Process	GO:0048386	positive regulation of retinoic acid receptor signaling pathway	IDA	J:114350
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:114350
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0035564	regulation of kidney size	IMP	J:229413
Biological Process	GO:0032526	response to retinoic acid	IDA	J:114350
Biological Process	GO:0048538	thymus development	IMP	J:155898