GO Annotations Graph

• Symbol: Xirp2
• Name: xin actin-binding repeat containing 2
• ID: MGI:2685198

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0003779	actin binding	IEA	J:72247
Molecular Function	GO:0051015	actin filament binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0051393	alpha-actinin binding	IDA	J:117604
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:255706
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Cellular Component	GO:0030054	cell junction	IEA	J:72247
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0001725	stress fiber	ISO	J:164563
Cellular Component	GO:0001725	stress fiber	IBA	J:265628
Cellular Component	GO:0030018	Z disc	IDA	J:117604
Biological Process	GO:0030036	actin cytoskeleton organization	IEA	J:72247
Biological Process	GO:0007015	actin filament organization	IBA	J:265628
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	IMP	J:158491
Biological Process	GO:0045216	cell-cell junction organization	IMP	J:158491
Biological Process	GO:0007507	heart development	IEA	J:72247
Biological Process	GO:0003281	ventricular septum development	IMP	J:158491