GO Annotations Graph

• Symbol: Ighe
• Name: Immunoglobulin heavy constant epsilon
• ID: MGI:2685746

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0034987	immunoglobulin receptor binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:252910
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0071744	IgE B cell receptor complex	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0090716	adaptive immune memory response	ISO	J:164563
Biological Process	GO:0001788	antibody-dependent cellular cytotoxicity	ISO	J:164563
Biological Process	GO:0002450	B cell antigen processing and presentation	ISO	J:164563
Biological Process	GO:0030183	B cell differentiation	IMP	J:252910
Biological Process	GO:0030183	B cell differentiation	IGI	J:252910
Biological Process	GO:0042100	B cell proliferation	ISO	J:164563
Biological Process	GO:0050853	B cell receptor signaling pathway	ISO	J:164563
Biological Process	GO:0043308	eosinophil degranulation	ISO	J:164563
Biological Process	GO:0160006	Fc receptor-mediated immune complex endocytosis	ISO	J:164563
Biological Process	GO:0002377	immunoglobulin production	IMP	J:252910
Biological Process	GO:0042116	macrophage activation	ISO	J:164563
Biological Process	GO:0030225	macrophage differentiation	ISO	J:164563
Biological Process	GO:0043303	mast cell degranulation	ISO	J:164563
Biological Process	GO:0090720	primary adaptive immune response	ISO	J:164563
Biological Process	GO:0042092	type 2 immune response	ISO	J:164563
Biological Process	GO:0016068	type I hypersensitivity	ISO	J:164563