GO Annotations Graph

• Symbol: Cracr2a
• Name: calcium release activated channel regulator 2A
• ID: MGI:2685919

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0005525	GTP binding	IEA	J:72247
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0000139	Golgi membrane	ISO	J:164563
Cellular Component	GO:0001772	immunological synapse	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005815	microtubule organizing center	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032588	trans-Golgi network membrane	ISO	J:164563
Cellular Component	GO:0031982	vesicle	ISO	J:164563
Cellular Component	GO:0033093	Weibel-Palade body	ISO	J:164563
Biological Process	GO:0032237	activation of store-operated calcium channel activity	ISO	J:164563
Biological Process	GO:0032237	activation of store-operated calcium channel activity	ISO	J:164563
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0006816	calcium ion transport	IEA	J:60000
Biological Process	GO:0016197	endosomal transport	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0051928	positive regulation of calcium ion transport	ISO	J:164563
Biological Process	GO:0046330	positive regulation of JNK cascade	IMP	J:259523
Biological Process	GO:0046330	positive regulation of JNK cascade	ISO	J:164563
Biological Process	GO:0034776	response to histamine	ISO	J:164563
Biological Process	GO:0002115	store-operated calcium entry	ISO	J:164563
Biological Process	GO:0045063	T-helper 1 cell differentiation	IMP	J:264324
Biological Process	GO:0045063	T-helper 1 cell differentiation	ISO	J:164563