GO Annotations Graph

• Symbol: Pld6
• Name: phospholipase D family member 6
• ID: MGI:2687283

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035755	cardiolipin hydrolase activity	ISO	J:164563
Molecular Function	GO:0003824	catalytic activity	IEA	J:72247
Molecular Function	GO:0004519	endonuclease activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	IPI	J:189220
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Molecular Function	GO:0004630	phospholipase D activity	TAS	Reactome:R-MMU-1483172
Molecular Function	GO:0005515	protein binding	IPI	J:221349
Molecular Function	GO:0005515	protein binding	IPI	J:278636
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TAS	Reactome:R-MMU-1483172
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	IDA	J:169934
Cellular Component	GO:0005741	mitochondrial outer membrane	TAS	Reactome:R-MMU-5605262
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0043046	DNA methylation involved in gamete generation	IMP	J:169934
Biological Process	GO:0016042	lipid catabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0051321	meiotic cell cycle	IMP	J:169934
Biological Process	GO:0051321	meiotic cell cycle	IMP	J:169933
Biological Process	GO:0008053	mitochondrial fusion	ISO	J:164563
Biological Process	GO:0030719	P granule organization	IMP	J:169933
Biological Process	GO:0034587	piRNA processing	IMP	J:169933
Biological Process	GO:0034587	piRNA processing	IMP	J:169934
Biological Process	GO:0034587	piRNA processing	IBA	J:265628
Biological Process	GO:0010636	positive regulation of mitochondrial fusion	ISO	J:73065
Biological Process	GO:0007286	spermatid development	IMP	J:169933
Biological Process	GO:0007286	spermatid development	IMP	J:169934
Biological Process	GO:0007283	spermatogenesis	IEA	J:60000