GO Annotations Graph

• Symbol: Mkx
• Name: mohawk homeobox
• ID: MGI:2687286

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	J:211235
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:211235
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:146223
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IMP	J:211235
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:211235
Molecular Function	GO:0005515	protein binding	IPI	J:146223
Molecular Function	GO:0005515	protein binding	IPI	J:146223
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:211235
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:146223
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:146223
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:146223
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IC	J:146223
Biological Process	GO:0048468	cell development	IBA	J:265628
Biological Process	GO:0071260	cellular response to mechanical stimulus	ISO	J:155856
Biological Process	GO:0030199	collagen fibril organization	IMP	J:175747
Biological Process	GO:0036077	intratendonous ossification	ISO	J:155856
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007517	muscle organ development	IEP	J:106154
Biological Process	GO:0007517	muscle organ development	IBA	J:265628
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	ISO	J:155856
Biological Process	GO:0045599	negative regulation of fat cell differentiation	ISO	J:155856
Biological Process	GO:0045662	negative regulation of myoblast differentiation	IDA	J:146223
Biological Process	GO:0030279	negative regulation of ossification	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:211235
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:146223
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	IMP	J:161299
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:175747
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:211235
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0010468	regulation of gene expression	IMP	J:161299
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0035990	tendon cell differentiation	ISO	J:155856
Biological Process	GO:0035990	tendon cell differentiation	IMP	J:175747
Biological Process	GO:0035992	tendon formation	IMP	J:175747
Biological Process	GO:0035992	tendon formation	IMP	J:167977
Biological Process	GO:0035992	tendon formation	IMP	J:167977
Biological Process	GO:0035992	tendon formation	IMP	J:175747
Biological Process	GO:0035992	tendon formation	IMP	J:161299
Biological Process	GO:0035992	tendon formation	IMP	J:167977
Biological Process	GO:0035992	tendon formation	IMP	J:175747
Biological Process	GO:0035992	tendon formation	IMP	J:167977
Biological Process	GO:0035992	tendon formation	IMP	J:167977
Biological Process	GO:0035992	tendon formation	IMP	J:167977
Biological Process	GO:0002932	tendon sheath development	IMP	J:175747