GO Annotations Graph

• Symbol: Cdhr2
• Name: cadherin-related family member 2
• ID: MGI:2687323

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0050839	cell adhesion molecule binding	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0005903	brush border	ISO	J:164563
Cellular Component	GO:0031526	brush border membrane	ISO	J:164563
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0031528	microvillus membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0098609	cell-cell adhesion	IEA	J:72247
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	ISO	J:164563
Biological Process	GO:0030855	epithelial cell differentiation	ISO	J:164563
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	IEA	J:72247
Biological Process	GO:0090675	intermicrovillar adhesion	ISO	J:164563
Biological Process	GO:0060243	negative regulation of cell growth involved in contact inhibition	ISO	J:164563
Biological Process	GO:0032532	regulation of microvillus length	ISO	J:164563