GO Annotations Graph

• Symbol: Chd5
• Name: chromodomain helicase DNA binding protein 5
• ID: MGI:3036258

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	IBA	J:265628
Molecular Function	GO:0140658	ATP-dependent chromatin remodeler activity	IBA	J:265628
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0003677	DNA binding	IBA	J:265628
Molecular Function	GO:0003678	DNA helicase activity	IEA	J:72247
Molecular Function	GO:0061628	H3K27me3 modified histone binding	ISO	J:164563
Molecular Function	GO:0061628	H3K27me3 modified histone binding	IDA	J:204443
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0042393	histone binding	IDA	J:207808
Molecular Function	GO:0042393	histone binding	IBA	J:265628
Molecular Function	GO:0042826	histone deacetylase binding	IPI	J:207814
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:207814
Cellular Component	GO:0000785	chromatin	ISO	J:155856
Cellular Component	GO:0000785	chromatin	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0000792	heterochromatin	IDA	J:207808
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:204443
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0016581	NuRD complex	IDA	J:207814
Cellular Component	GO:0016581	NuRD complex	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0021895	cerebral cortex neuron differentiation	IMP	J:204443
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	IBA	J:265628
Biological Process	GO:0098532	histone H3-K27 trimethylation	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:207808
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:121726
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:207808
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:1901798	positive regulation of signal transduction by p53 class mediator	IMP	J:121726
Biological Process	GO:0045595	regulation of cell differentiation	IMP	J:207808
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0035092	sperm DNA condensation	IMP	J:207846
Biological Process	GO:0007283	spermatogenesis	IEA	J:60000
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:155856