GO Annotations Graph

• Symbol: Piwil4
• Name: piwi-like RNA-mediated gene silencing 4
• ID: MGI:3041167

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0034584	piRNA binding	IDA	J:141096
Molecular Function	GO:0034584	piRNA binding	ISO	J:164563
Molecular Function	GO:0034584	piRNA binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:156018
Molecular Function	GO:0005515	protein binding	IPI	J:197673
Molecular Function	GO:0005515	protein binding	IPI	J:295943
Molecular Function	GO:0005515	protein binding	IPI	J:161125
Molecular Function	GO:0005515	protein binding	IPI	J:291848
Molecular Function	GO:0005515	protein binding	IPI	J:161124
Molecular Function	GO:0005515	protein binding	IPI	J:112036
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:141096
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5606210
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5606252
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5606256
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5629230
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5606256
Cellular Component	GO:0005634	nucleus	IDA	J:141096
Cellular Component	GO:0005634	nucleus	IDA	J:295943
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:288732
Cellular Component	GO:0005634	nucleus	IDA	J:291848
Cellular Component	GO:0043186	P granule	IDA	J:141096
Cellular Component	GO:0043186	P granule	IBA	J:265628
Cellular Component	GO:0071547	piP-body	IDA	J:156018
Cellular Component	GO:0071547	piP-body	IDA	J:155865
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0043046	DNA methylation involved in gamete generation	IMP	J:141096
Biological Process	GO:0043046	DNA methylation involved in gamete generation	IMP	J:133343
Biological Process	GO:0010669	epithelial structure maintenance	ISO	J:164563
Biological Process	GO:0051321	meiotic cell cycle	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0010529	negative regulation of transposition	IMP	J:184034
Biological Process	GO:0010529	negative regulation of transposition	IMP	J:225677
Biological Process	GO:0034587	piRNA processing	IDA	J:141096
Biological Process	GO:0034587	piRNA processing	IDA	J:229314
Biological Process	GO:0034587	piRNA processing	IMP	J:133343
Biological Process	GO:0034587	piRNA processing	IMP	J:184034
Biological Process	GO:0034587	piRNA processing	IMP	J:120824
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0006417	regulation of translation	IEA	J:60000
Biological Process	GO:0031047	RNA-mediated gene silencing	IMP	J:141096
Biological Process	GO:0031047	RNA-mediated gene silencing	IMP	J:120824
Biological Process	GO:0031047	RNA-mediated gene silencing	IMP	J:133343
Biological Process	GO:0031047	RNA-mediated gene silencing	IBA	J:265628
Biological Process	GO:0007283	spermatogenesis	IMP	J:120824
Biological Process	GO:0007283	spermatogenesis	IMP	J:184034
Biological Process	GO:0007283	spermatogenesis	IMP	J:133343
Biological Process	GO:0007283	spermatogenesis	IMP	J:225677