GO Annotations Graph

• Symbol: Traf7
• Name: TNF receptor-associated factor 7
• ID: MGI:3042141

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:107109
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:107109
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:107109
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IDA	J:107109
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0000151	ubiquitin ligase complex	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	ISO	J:89527
Biological Process	GO:0071354	cellular response to interleukin-6	IDA	J:107109
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:107109
Biological Process	GO:0007219	Notch signaling pathway	IBA	J:265628
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:89527
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0033235	positive regulation of protein sumoylation	IDA	J:107109
Biological Process	GO:0016567	protein ubiquitination	ISO	J:164563
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0032880	regulation of protein localization	IDA	J:107109
Biological Process	GO:0000027	ribosomal large subunit assembly	IBA	J:265628