GO Annotations Graph

• Symbol: Gsdma3
• Name: gasdermin A3
• ID: MGI:3044668

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:1901612	cardiolipin binding	IDA	J:296115
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	IBA	J:265628
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	IBA	J:265628
Molecular Function	GO:0001786	phosphatidylserine binding	IBA	J:265628
Molecular Function	GO:0005543	phospholipid binding	IDA	J:296107
Molecular Function	GO:0022829	wide pore channel activity	ISO	J:164563
Molecular Function	GO:0022829	wide pore channel activity	IDA	J:326912
Molecular Function	GO:0022829	wide pore channel activity	IDA	J:296107
Molecular Function	GO:0022829	wide pore channel activity	IDA	J:319941
Molecular Function	GO:0022829	wide pore channel activity	IDA	J:296115
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:296107
Cellular Component	GO:0016020	membrane	IDA	J:326912
Cellular Component	GO:0016020	membrane	IDA	J:296115
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IDA	J:296104
Cellular Component	GO:0005634	nucleus	IDA	J:225546
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:296107
Biological Process	GO:0042640	anagen	IMP	J:122738
Biological Process	GO:0036331	avascular cornea development in camera-type eye	IMP	J:47847
Biological Process	GO:0042637	catagen	IMP	J:189395
Biological Process	GO:0042637	catagen	IMP	J:93938
Biological Process	GO:0042637	catagen	IMP	J:96427
Biological Process	GO:0042742	defense response to bacterium	ISO	J:164563
Biological Process	GO:0042742	defense response to bacterium	IBA	J:265628
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IDA	J:189571
Biological Process	GO:0042633	hair cycle	IMP	J:78078
Biological Process	GO:0001942	hair follicle development	IMP	J:296134
Biological Process	GO:0001942	hair follicle development	IMP	J:166522
Biological Process	GO:0001942	hair follicle development	IMP	J:42692
Biological Process	GO:0001942	hair follicle development	IMP	J:96427
Biological Process	GO:0031069	hair follicle morphogenesis	IMP	J:93938
Biological Process	GO:0030879	mammary gland development	IMP	J:296134
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IDA	J:225546
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	IMP	J:225546
Biological Process	GO:0051886	negative regulation of timing of anagen	IDA	J:225546
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:189395
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	IDA	J:189571
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IDA	J:319941
Biological Process	GO:0012501	programmed cell death	IMP	J:296104
Biological Process	GO:0012501	programmed cell death	IMP	J:296133
Biological Process	GO:0051259	protein complex oligomerization	IDA	J:296115
Biological Process	GO:0051259	protein complex oligomerization	IDA	J:296107
Biological Process	GO:0051259	protein complex oligomerization	IDA	J:326912
Biological Process	GO:0070269	pyroptosis	ISO	J:164563
Biological Process	GO:0070269	pyroptosis	IDA	J:326912
Biological Process	GO:0070269	pyroptosis	IDA	J:296107
Biological Process	GO:0070269	pyroptosis	IDA	J:296115
Biological Process	GO:0070269	pyroptosis	IBA	J:265628
Biological Process	GO:0001949	sebaceous gland cell differentiation	IMP	J:96427
Biological Process	GO:0043588	skin development	IMP	J:47847
Biological Process	GO:0043588	skin development	IMP	J:42692
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:180149