GO Annotations Graph

• Symbol: Unc13a
• Name: unc-13 homolog A
• ID: MGI:3051532

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0005516	calmodulin binding	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	IBA	J:265628
Molecular Function	GO:0005516	calmodulin binding	IDA	J:282820
Molecular Function	GO:0019992	diacylglycerol binding	IDA	J:91545
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005543	phospholipid binding	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:159767
Molecular Function	GO:0005515	protein binding	IPI	J:153882
Molecular Function	GO:0005515	protein binding	IPI	J:57874
Molecular Function	GO:0005515	protein binding	IPI	J:153882
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Molecular Function	GO:0030507	spectrin binding	ISO	J:155856
Molecular Function	GO:0019905	syntaxin binding	ISO	J:155856
Molecular Function	GO:0017075	syntaxin-1 binding	ISO	J:155856
Molecular Function	GO:0017075	syntaxin-1 binding	IBA	J:265628
Cellular Component	GO:0030424	axon	IDA	J:201692
Cellular Component	GO:0044305	calyx of Held	IDA	J:197134
Cellular Component	GO:0044305	calyx of Held	IDA	J:197134
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0060076	excitatory synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:56513
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:56513
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:56513
Cellular Component	GO:0005798	Golgi-associated vesicle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031594	neuromuscular junction	IBA	J:265628
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:99336
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0098793	presynapse	IDA	J:56513
Cellular Component	GO:0098793	presynapse	IDA	J:223843
Cellular Component	GO:0048786	presynaptic active zone	ISO	J:155856
Cellular Component	GO:0048786	presynaptic active zone	IC	J:74343
Cellular Component	GO:0048786	presynaptic active zone	IDA	J:197134
Cellular Component	GO:0048786	presynaptic active zone	IDA	J:197134
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	ISO	J:155856
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	IBA	J:265628
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0045202	synapse	IDA	J:56513
Cellular Component	GO:0045202	synapse	IDA	J:201692
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	IBA	J:265628
Cellular Component	GO:0043195	terminal bouton	IBA	J:265628
Biological Process	GO:0050435	amyloid-beta metabolic process	IMP	J:91545
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0007268	chemical synaptic transmission	IEA	J:72247
Biological Process	GO:0061789	dense core granule priming	ISO	J:155856
Biological Process	GO:0061789	dense core granule priming	IBA	J:265628
Biological Process	GO:0006887	exocytosis	IEA	J:60000
Biological Process	GO:0060384	innervation	IGI	J:99336
Biological Process	GO:0060291	long-term synaptic potentiation	ISO	J:155856
Biological Process	GO:0007528	neuromuscular junction development	IBA	J:265628
Biological Process	GO:0007528	neuromuscular junction development	IGI	J:99336
Biological Process	GO:0099011	neuronal dense core vesicle exocytosis	IMP	J:195236
Biological Process	GO:0007269	neurotransmitter secretion	ISO	J:155856
Biological Process	GO:0007269	neurotransmitter secretion	IMP	J:74347
Biological Process	GO:0007269	neurotransmitter secretion	IMP	J:74347
Biological Process	GO:1903861	positive regulation of dendrite extension	ISO	J:164563
Biological Process	GO:1900451	positive regulation of glutamate receptor signaling pathway	IMP	J:235255
Biological Process	GO:0001956	positive regulation of neurotransmitter secretion	IMP	J:74347
Biological Process	GO:0031915	positive regulation of synaptic plasticity	IGI	J:197134
Biological Process	GO:0099525	presynaptic dense core vesicle exocytosis	IGI	J:238441
Biological Process	GO:0099525	presynaptic dense core vesicle exocytosis	IBA	J:265628
Biological Process	GO:1902991	regulation of amyloid precursor protein catabolic process	IMP	J:235255
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	IMP	J:74343
Biological Process	GO:0010807	regulation of synaptic vesicle priming	ISO	J:155856
Biological Process	GO:0010807	regulation of synaptic vesicle priming	TAS	J:111069
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IBA	J:265628
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IGI	J:74347
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IMP	J:74343
Biological Process	GO:0016081	synaptic vesicle docking	IBA	J:265628
Biological Process	GO:0016081	synaptic vesicle docking	IGI	J:151675
Biological Process	GO:0016079	synaptic vesicle exocytosis	IDA	J:56513
Biological Process	GO:0016079	synaptic vesicle exocytosis	IMP	J:56513
Biological Process	GO:0016079	synaptic vesicle exocytosis	IDA	J:56513
Biological Process	GO:0016188	synaptic vesicle maturation	IBA	J:265628
Biological Process	GO:0016188	synaptic vesicle maturation	IMP	J:56513
Biological Process	GO:0016082	synaptic vesicle priming	IGI	J:218225
Biological Process	GO:0016082	synaptic vesicle priming	NAS	J:197134
Biological Process	GO:0016082	synaptic vesicle priming	IMP	J:74343
Biological Process	GO:0016082	synaptic vesicle priming	ISO	J:155856
Biological Process	GO:0016082	synaptic vesicle priming	IBA	J:265628