GO Annotations Graph

• Symbol: Spef1
• Name: sperm flagellar 1
• ID: MGI:3513546

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	IMP	J:277764
Molecular Function	GO:0008017	microtubule binding	IDA	J:243402
Molecular Function	GO:0008017	microtubule binding	IBA	J:265628
Cellular Component	GO:0097729	9+2 motile cilium	IDA	J:277764
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:1990716	axonemal central apparatus	IDA	J:277764
Cellular Component	GO:0005930	axoneme	IBA	J:265628
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0097542	ciliary tip	IDA	J:277764
Cellular Component	GO:0005929	cilium	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:99330
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0030175	filopodium	ISO	J:164563
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0005902	microvillus	ISO	J:164563
Cellular Component	GO:0031514	motile cilium	IDA	J:99330
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Biological Process	GO:1904158	axonemal central apparatus assembly	IMP	J:277764
Biological Process	GO:0030030	cell projection organization	IEA	J:60000
Biological Process	GO:0003341	cilium movement	IMP	J:277764
Biological Process	GO:0046847	filopodium assembly	ISO	J:164563
Biological Process	GO:0030032	lamellipodium assembly	ISO	J:164563
Biological Process	GO:0001578	microtubule bundle formation	IDA	J:277764
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	IDA	J:243402
Biological Process	GO:0051493	regulation of cytoskeleton organization	IBA	J:265628