GO Annotations Graph

• Symbol: Kdm4d
• Name: lysine (K)-specific demethylase 4D
• ID: MGI:3606484

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:6795
Molecular Function	GO:0003684	damaged DNA binding	IDA	J:206795
Molecular Function	GO:0051213	dioxygenase activity	IEA	J:60000
Molecular Function	GO:0032452	histone demethylase activity	IDA	J:148615
Molecular Function	GO:0032454	histone H3K9 demethylase activity	ISO	J:164563
Molecular Function	GO:0032454	histone H3K9 demethylase activity	IBA	J:265628
Molecular Function	GO:0032454	histone H3K9 demethylase activity	IMP	J:173703
Molecular Function	GO:0032454	histone H3K9 demethylase activity	IDA	J:109728
Molecular Function	GO:0032454	histone H3K9 demethylase activity	IMP	J:206795
Molecular Function	GO:0140684	histone H3K9me2/H3K9me3 demethylase activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:206795
Cellular Component	GO:0005721	pericentric heterochromatin	IDA	J:109728
Cellular Component	GO:0035861	site of double-strand break	ISO	J:206795
Cellular Component	GO:0035861	site of double-strand break	IDA	J:206795
Biological Process	GO:0071479	cellular response to ionizing radiation	ISO	J:206795
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	IDA	J:206795
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ISO	J:206795
Biological Process	GO:0016570	histone modification	IDA	J:148615
Biological Process	GO:0035563	positive regulation of chromatin binding	ISO	J:206795
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	ISO	J:206795
Biological Process	GO:0001932	regulation of protein phosphorylation	ISO	J:206795