GO Annotations Graph

• Symbol: Btn2a2
• Name: butyrophilin, subfamily 2, member A2
• ID: MGI:3606486

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005102	signaling receptor binding	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:202549
Cellular Component	GO:0009986	cell surface	IDA	J:202549
Cellular Component	GO:0009986	cell surface	IDA	J:202549
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IDA	J:202549
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	IDA	J:202549
Biological Process	GO:0046007	negative regulation of activated T cell proliferation	IDA	J:160063
Biological Process	GO:0046007	negative regulation of activated T cell proliferation	IDA	J:202549
Biological Process	GO:0001818	negative regulation of cytokine production	IDA	J:160063
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	IDA	J:202549
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	IDA	J:202549
Biological Process	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	IGI	J:202549
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IGI	J:202549
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	IDA	J:202549
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	IGI	J:202549
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	IDA	J:202549
Biological Process	GO:0043491	protein kinase B signaling	IGI	J:202549
Biological Process	GO:0001817	regulation of cytokine production	IBA	J:265628
Biological Process	GO:0050852	T cell receptor signaling pathway	IBA	J:265628