GO Annotations Graph

• Symbol: Gfral
• Name: GDNF family receptor alpha like
• ID: MGI:3607786

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016167	glial cell-derived neurotrophic factor receptor activity	IDA	J:251850
Molecular Function	GO:0016167	glial cell-derived neurotrophic factor receptor activity	IDA	J:251981
Molecular Function	GO:0016167	glial cell-derived neurotrophic factor receptor activity	ISO	J:164563
Molecular Function	GO:0016167	glial cell-derived neurotrophic factor receptor activity	IDA	J:251855
Molecular Function	GO:0005515	protein binding	IPI	J:251981
Molecular Function	GO:0005515	protein binding	IPI	J:251850
Molecular Function	GO:0030971	receptor tyrosine kinase binding	IPI	J:251981
Molecular Function	GO:0030971	receptor tyrosine kinase binding	ISO	J:164563
Molecular Function	GO:0038023	signaling receptor activity	IBA	J:265628
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	ISO	J:164563
Cellular Component	GO:0009897	external side of plasma membrane	IBA	J:265628
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:103510
Cellular Component	GO:0043235	receptor complex	IBA	J:265628
Biological Process	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	IDA	J:103510
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IDA	J:103510
Biological Process	GO:0007399	nervous system development	IBA	J:265628
Biological Process	GO:0043410	positive regulation of MAPK cascade	IMP	J:254140
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0002023	reduction of food intake in response to dietary excess	IMP	J:251850
Biological Process	GO:0002023	reduction of food intake in response to dietary excess	IMP	J:254140
Biological Process	GO:0002023	reduction of food intake in response to dietary excess	IDA	J:251855
Biological Process	GO:0002023	reduction of food intake in response to dietary excess	IMP	J:251981
Biological Process	GO:0031098	stress-activated protein kinase signaling cascade	IDA	J:103510