GO Annotations Graph

• Symbol: Scimp
• Name: SLP adaptor and CSK interacting membrane protein
• ID: MGI:3610314

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0060090	molecular adaptor activity	IMP	J:244275
Molecular Function	GO:0005515	protein binding	IPI	J:276512
Molecular Function	GO:0005515	protein binding	IPI	J:178776
Molecular Function	GO:0005515	protein binding	IPI	J:244275
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0030175	filopodium	IMP	J:244275
Cellular Component	GO:0001772	immunological synapse	ISO	J:164563
Cellular Component	GO:0001772	immunological synapse	IBA	J:265628
Cellular Component	GO:0031256	leading edge membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0045335	phagocytic vesicle	IMP	J:235794
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0043235	receptor complex	IDA	J:244275
Cellular Component	GO:0001726	ruffle	IMP	J:244275
Cellular Component	GO:0097197	tetraspanin-enriched microdomain	ISO	J:164563
Cellular Component	GO:0031259	uropod membrane	ISO	J:164563
Biological Process	GO:0071226	cellular response to molecule of fungal origin	IMP	J:235794
Biological Process	GO:0002720	positive regulation of cytokine production involved in immune response	IMP	J:235794
Biological Process	GO:0002732	positive regulation of dendritic cell cytokine production	IMP	J:235794
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IMP	J:178776
Biological Process	GO:0032735	positive regulation of interleukin-12 production	IMP	J:244275
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IMP	J:244275
Biological Process	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	IDA	J:244275
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	IMP	J:235794
Biological Process	GO:0034138	toll-like receptor 3 signaling pathway	IMP	J:244275
Biological Process	GO:0034142	toll-like receptor 4 signaling pathway	IMP	J:244275
Biological Process	GO:0034154	toll-like receptor 7 signaling pathway	IMP	J:244275
Biological Process	GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	IMP	J:244275