GO Annotations Graph

• Symbol: Cyp4a12b
• Name: cytochrome P450, family 4, subfamily a, polypeptide 12B
• ID: MGI:3611747

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0103002	16-hydroxypalmitate dehydrogenase activity	ISO	J:164563
Molecular Function	GO:0018685	alkane 1-monooxygenase activity	ISO	J:164563
Molecular Function	GO:0018685	alkane 1-monooxygenase activity	IBA	J:265628
Molecular Function	GO:0008392	arachidonic acid epoxygenase activity	ISO	J:164563
Molecular Function	GO:0008391	arachidonic acid monooxygenase activity	IBA	J:265628
Molecular Function	GO:0052869	arachidonic acid omega-hydroxylase activity	IDA	J:121394
Molecular Function	GO:0070330	aromatase activity	IEA	J:72245
Molecular Function	GO:0120250	fatty acid omega-hydroxylase activity	ISO	J:155856
Molecular Function	GO:0020037	heme binding	IEA	J:72247
Molecular Function	GO:0005506	iron ion binding	IEA	J:72247
Molecular Function	GO:0050051	leukotriene-B4 20-monooxygenase activity	ISO	J:164563
Molecular Function	GO:0102033	long-chain fatty acid omega-hydroxylase activity	ISO	J:164563
Molecular Function	GO:0140981	medium-chain fatty acid omega-hydroxylase activity	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004497	monooxygenase activity	ISO	J:155856
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA	J:72247
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0019369	arachidonic acid metabolic process	ISO	J:164563
Biological Process	GO:0019369	arachidonic acid metabolic process	ISO	J:155856
Biological Process	GO:0019369	arachidonic acid metabolic process	IBA	J:265628
Biological Process	GO:0019373	epoxygenase P450 pathway	ISO	J:164563
Biological Process	GO:0006631	fatty acid metabolic process	ISO	J:155856
Biological Process	GO:0046456	icosanoid biosynthetic process	IBA	J:265628
Biological Process	GO:0001822	kidney development	IBA	J:265628
Biological Process	GO:0048252	lauric acid metabolic process	ISO	J:155856
Biological Process	GO:0048252	lauric acid metabolic process	IBA	J:265628
Biological Process	GO:0006691	leukotriene metabolic process	ISO	J:164563
Biological Process	GO:0043651	linoleic acid metabolic process	IBA	J:265628
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ISO	J:164563
Biological Process	GO:0097267	omega-hydroxylase P450 pathway	IDA	J:121394
Biological Process	GO:0032305	positive regulation of icosanoid secretion	ISO	J:164563