Shank1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Shank1
SH3 and multiple ankyrin repeat domains 1
MGI:3613677

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071532	ankyrin repeat binding	ISO	J:155856
Molecular Function	GO:0001664	G protein-coupled receptor binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	ISO	J:155856
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	IPI	J:150922
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	IPI	J:108736
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:173460
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Molecular Function	GO:0017124	SH3 domain binding	ISO	J:155856
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	ISO	J:155856
Molecular Function	GO:0031877	somatostatin receptor binding	ISO	J:155856
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IDA	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IDA	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IDA	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IMP	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IMP	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IDA	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IDA	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IEP	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IDA	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IEP	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IDA	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IDA	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IDA	J:132277
Molecular Function	GO:0098919	structural constituent of postsynaptic density	IDA	J:132277
Molecular Function	GO:0030160	synaptic receptor adaptor activity	IMP	J:132277
Molecular Function	GO:0030160	synaptic receptor adaptor activity	ISO	J:155856
Molecular Function	GO:0030160	synaptic receptor adaptor activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0030425	dendrite	IDA	J:177124
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	IDA	J:150922
Cellular Component	GO:0043197	dendritic spine	IBA	J:265628
Cellular Component	GO:0060076	excitatory synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IEP	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IEP	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:132277
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	IDA	J:184110
Cellular Component	GO:0005886	plasma membrane	IDA	J:150922
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IDA	J:237681
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	IDA	J:132277
Cellular Component	GO:0014069	postsynaptic density	IDA	J:132277
Cellular Component	GO:0014069	postsynaptic density	IDA	J:132277
Cellular Component	GO:0014069	postsynaptic density	IDA	J:132277
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:150922
Cellular Component	GO:0045211	postsynaptic membrane	IBA	J:265628
Cellular Component	GO:0045211	postsynaptic membrane	IDA	J:101566
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IEP	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IEP	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:132277
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:132277
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0030534	adult behavior	ISO	J:164563
Biological Process	GO:0008306	associative learning	IMP	J:132277
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0060997	dendritic spine morphogenesis	IMP	J:132277
Biological Process	GO:0050894	determination of affect	ISO	J:164563
Biological Process	GO:0046959	habituation	IMP	J:174446
Biological Process	GO:0007616	long-term memory	IMP	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IEP	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IMP	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IEP	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:132277
Biological Process	GO:0050804	modulation of chemical synaptic transmission	IDA	J:132277
Biological Process	GO:0032232	negative regulation of actin filament bundle assembly	IDA	J:148808
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:170750
Biological Process	GO:0042048	olfactory behavior	IMP	J:174446
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	IMP	J:132277
Biological Process	GO:0035418	protein localization to synapse	IMP	J:132277
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:155856
Biological Process	GO:2000311	regulation of AMPA receptor activity	IMP	J:132277
Biological Process	GO:0060013	righting reflex	IMP	J:174446
Biological Process	GO:0035176	social behavior	IMP	J:174446
Biological Process	GO:0035176	social behavior	ISO	J:164563
Biological Process	GO:0060074	synapse maturation	ISO	J:155856
Biological Process	GO:0071625	vocalization behavior	ISO	J:164563
Biological Process	GO:0071625	vocalization behavior	IMP	J:174446

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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