GO Annotations Graph

• Symbol: Pnpla1
• Name: patatin-like phospholipase domain containing 1
• ID: MGI:3617850

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	ISO	J:164563
Molecular Function	GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	IMP	J:240053
Molecular Function	GO:0016787	hydrolase activity	IEA	J:72247
Molecular Function	GO:0106341	omega-hydroxyceramide transacylase activity	IMP	J:240682
Molecular Function	GO:0106341	omega-hydroxyceramide transacylase activity	ISO	J:164563
Molecular Function	GO:0030280	structural constituent of skin epidermis	IMP	J:240053
Molecular Function	GO:0030280	structural constituent of skin epidermis	IMP	J:240682
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004806	triglyceride lipase activity	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005811	lipid droplet	IBA	J:265628
Cellular Component	GO:0016020	membrane	IBA	J:265628
Biological Process	GO:0046513	ceramide biosynthetic process	ISO	J:164563
Biological Process	GO:0046513	ceramide biosynthetic process	IMP	J:240053
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:240053
Biological Process	GO:0061436	establishment of skin barrier	IMP	J:240682
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:240682
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:240053
Biological Process	GO:0016042	lipid catabolic process	IEA	J:72247
Biological Process	GO:0055088	lipid homeostasis	IBA	J:265628
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0006629	lipid metabolic process	IEA	J:72247
Biological Process	GO:0106342	omega-hydroxyceramide biosynthetic process	IMP	J:240682
Biological Process	GO:0106342	omega-hydroxyceramide biosynthetic process	ISO	J:164563
Biological Process	GO:0019433	triglyceride catabolic process	IBA	J:265628