GO Annotations Graph

• Symbol: Skor2
• Name: SKI family transcriptional corepressor 2
• ID: MGI:3645984

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:208769
Molecular Function	GO:0003682	chromatin binding	IDA	J:208769
Molecular Function	GO:0003682	chromatin binding	IDA	J:208769
Molecular Function	GO:0003682	chromatin binding	IDA	J:208769
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0042826	histone deacetylase binding	IPI	J:178818
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0046332	SMAD binding	ISO	J:164563
Molecular Function	GO:0046332	SMAD binding	IBA	J:265628
Molecular Function	GO:0046332	SMAD binding	IPI	J:178818
Molecular Function	GO:0046332	SMAD binding	IPI	J:178818
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:137604
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:178818
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Biological Process	GO:0048468	cell development	IMP	J:208769
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IMP	J:178818
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IMP	J:208769
Biological Process	GO:0021587	cerebellum morphogenesis	IMP	J:178818
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IBA	J:265628
Biological Process	GO:0030514	negative regulation of BMP signaling pathway	IGI	J:178818
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:137604
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:178818
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	IMP	J:178818
Biological Process	GO:0021936	regulation of cerebellar granule cell precursor proliferation	IMP	J:178818
Biological Process	GO:0048814	regulation of dendrite morphogenesis	IMP	J:178818
Biological Process	GO:1902692	regulation of neuroblast proliferation	IMP	J:178818
Biological Process	GO:0007224	smoothened signaling pathway	IMP	J:178818