GO Annotations Graph

• Symbol: Sh3gl2
• Name: SH3-domain GRB2-like 2
• ID: MGI:700009

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	IPI	J:247406
Molecular Function	GO:0008289	lipid binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:239200
Molecular Function	GO:0005515	protein binding	IPI	J:116685
Molecular Function	GO:0005515	protein binding	IPI	J:152583
Molecular Function	GO:0005515	protein binding	IPI	J:156815
Molecular Function	GO:0005515	protein binding	IPI	J:152583
Molecular Function	GO:0005515	protein binding	IPI	J:136888
Molecular Function	GO:0005515	protein binding	IPI	J:108456
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Cellular Component	GO:0097441	basal dendrite	ISO	J:155856
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:72247
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005769	early endosome	IDA	J:239200
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0098978	glutamatergic synapse	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:311147
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:311147
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:311147
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:311147
Cellular Component	GO:0098978	glutamatergic synapse	IEP	J:311147
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:311147
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:311147
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:311147
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:311147
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:311147
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0098684	photoreceptor ribbon synapse	IDA	J:199646
Cellular Component	GO:0098684	photoreceptor ribbon synapse	IDA	J:199646
Cellular Component	GO:0098794	postsynapse	IDA	J:311147
Cellular Component	GO:0098794	postsynapse	IDA	J:311147
Cellular Component	GO:0098794	postsynapse	IDA	J:311147
Cellular Component	GO:0098794	postsynapse	IDA	J:311147
Cellular Component	GO:0098794	postsynapse	IDA	J:311147
Cellular Component	GO:0098794	postsynapse	IEP	J:311147
Cellular Component	GO:0098793	presynapse	ISO	J:155856
Cellular Component	GO:0098793	presynapse	IBA	J:265628
Cellular Component	GO:0099523	presynaptic cytosol	IDA	J:199646
Cellular Component	GO:0099523	presynaptic cytosol	IDA	J:199646
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	IMP	J:239200
Biological Process	GO:0097484	dendrite extension	IMP	J:239200
Biological Process	GO:0006897	endocytosis	IEA	J:60000
Biological Process	GO:0060988	lipid tube assembly	ISO	J:155856
Biological Process	GO:0097753	membrane bending	ISO	J:155856
Biological Process	GO:0097749	membrane tubulation	ISO	J:155856
Biological Process	GO:1905604	negative regulation of blood-brain barrier permeability	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0001933	negative regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0031175	neuron projection development	IMP	J:239200
Biological Process	GO:1903527	positive regulation of membrane tubulation	ISO	J:155856
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IDA	J:311147
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IDA	J:311147
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IMP	J:311147
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	IDA	J:311147
Biological Process	GO:2000369	regulation of clathrin-dependent endocytosis	ISO	J:155856
Biological Process	GO:0002090	regulation of receptor internalization	IDA	J:108456
Biological Process	GO:0048488	synaptic vesicle endocytosis	ISO	J:155856
Biological Process	GO:0048488	synaptic vesicle endocytosis	IGI	J:152583
Biological Process	GO:0016191	synaptic vesicle uncoating	IGI	J:178947
Biological Process	GO:0016191	synaptic vesicle uncoating	IBA	J:265628
Biological Process	GO:0099050	vesicle scission	ISO	J:155856