Abl2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Abl2
ABL proto-oncogene 2, non-receptor tyrosine kinase
MGI:87860

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0000287	magnesium ion binding	IDA	J:116250
Molecular Function	GO:0030145	manganese ion binding	IDA	J:116250
Molecular Function	GO:0030145	manganese ion binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	IEA	J:72245
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0001784	phosphotyrosine residue binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:149136
Molecular Function	GO:0005515	protein binding	IPI	J:182501
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	ISO	J:164563
Molecular Function	GO:0004713	protein tyrosine kinase activity	IDA	J:116250
Molecular Function	GO:0004713	protein tyrosine kinase activity	IBA	J:265628
Molecular Function	GO:0004713	protein tyrosine kinase activity	IDA	J:140959
Molecular Function	GO:0004713	protein tyrosine kinase activity	IGI	J:164680
Molecular Function	GO:0004713	protein tyrosine kinase activity	IDA	J:90071
Molecular Function	GO:0004713	protein tyrosine kinase activity	IGI	J:164680
Molecular Function	GO:0004713	protein tyrosine kinase activity	IGI	J:140959
Molecular Function	GO:0004713	protein tyrosine kinase activity	IDA	J:190676
Molecular Function	GO:0004713	protein tyrosine kinase activity	IMP	J:90071
Molecular Function	GO:0004713	protein tyrosine kinase activity	IDA	J:149136
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:73441
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	TAS	J:72871
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0043197	dendritic spine	IDA	J:193891
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:234334
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:234334
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:234334
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:193891
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:193891
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:193891
Cellular Component	GO:0030027	lamellipodium	IDA	J:149136
Cellular Component	GO:0001891	phagocytic cup	IDA	J:190676
Cellular Component	GO:0098794	postsynapse	IMP	J:193891
Cellular Component	GO:0098794	postsynapse	IDA	J:193891
Cellular Component	GO:0098794	postsynapse	IDA	J:193891
Biological Process	GO:0030036	actin cytoskeleton organization	IDA	J:73441
Biological Process	GO:0030036	actin cytoskeleton organization	IGI	J:51887
Biological Process	GO:0051017	actin filament bundle assembly	IDA	J:73441
Biological Process	GO:0007015	actin filament organization	IDA	J:73441
Biological Process	GO:0007628	adult walking behavior	IMP	J:51887
Biological Process	GO:0002118	aggressive behavior	IMP	J:51887
Biological Process	GO:0046632	alpha-beta T cell differentiation	IGI	J:154821
Biological Process	GO:0031223	auditory behavior	IMP	J:51887
Biological Process	GO:0060020	Bergmann glial cell differentiation	IGI	J:166211
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0098609	cell-cell adhesion	IGI	J:211130
Biological Process	GO:0098609	cell-cell adhesion	IGI	J:211130
Biological Process	GO:0071300	cellular response to retinoic acid	ISO	J:164563
Biological Process	GO:0021587	cerebellum morphogenesis	IGI	J:166211
Biological Process	GO:0072359	circulatory system development	IGI	J:51887
Biological Process	GO:0048813	dendrite morphogenesis	IMP	J:193891
Biological Process	GO:0048813	dendrite morphogenesis	IGI	J:182501
Biological Process	GO:0048813	dendrite morphogenesis	IGI	J:193891
Biological Process	GO:0097062	dendritic spine maintenance	IGI	J:193891
Biological Process	GO:0097062	dendritic spine maintenance	IMP	J:193891
Biological Process	GO:1904157	DN4 thymocyte differentiation	IGI	J:154821
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	IGI	J:140959
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	IGI	J:140959
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:186633
Biological Process	GO:0051649	establishment of localization in cell	IGI	J:190676
Biological Process	GO:0035640	exploration behavior	IGI	J:196653
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	IGI	J:154821
Biological Process	GO:0007612	learning	IMP	J:153211
Biological Process	GO:0035264	multicellular organism growth	IMP	J:51887
Biological Process	GO:0022408	negative regulation of cell-cell adhesion	IGI	J:211130
Biological Process	GO:0022408	negative regulation of cell-cell adhesion	IGI	J:211130
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	IGI	J:198786
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:182501
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:90071
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:182501
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0001843	neural tube closure	IGI	J:51887
Biological Process	GO:0060563	neuroepithelial cell differentiation	IGI	J:51887
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:51887
Biological Process	GO:0050885	neuromuscular process controlling balance	IGI	J:166211
Biological Process	GO:0030182	neuron differentiation	IGI	J:51887
Biological Process	GO:0016322	neuron remodeling	IMP	J:153211
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IDA	J:116250
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ISO	J:164563
Biological Process	GO:0006909	phagocytosis	IMP	J:186633
Biological Process	GO:0006909	phagocytosis	IGI	J:190676
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	IGI	J:140959
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:73065
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IGI	J:140959
Biological Process	GO:1903905	positive regulation of establishment of T cell polarity	IMP	J:259787
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IGI	J:154821
Biological Process	GO:0032743	positive regulation of interleukin-2 production	IGI	J:154821
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	IGI	J:90071
Biological Process	GO:0051353	positive regulation of oxidoreductase activity	ISO	J:164563
Biological Process	GO:0010863	positive regulation of phospholipase C activity	ISO	J:73065
Biological Process	GO:0032092	positive regulation of protein binding	IMP	J:90071
Biological Process	GO:2000406	positive regulation of T cell migration	IMP	J:259787
Biological Process	GO:0032729	positive regulation of type II interferon production	IGI	J:154821
Biological Process	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway	IGI	J:164680
Biological Process	GO:0009791	post-embryonic development	IGI	J:51887
Biological Process	GO:0008104	protein localization	IMP	J:193891
Biological Process	GO:0006468	protein phosphorylation	IDA	J:116250
Biological Process	GO:0042981	regulation of apoptotic process	IBA	J:265628
Biological Process	GO:1903053	regulation of extracellular matrix organization	IGI	J:166211
Biological Process	GO:0022414	reproductive process	IMP	J:51887
Biological Process	GO:0007266	Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0007266	Rho protein signal transduction	IGI	J:196653
Biological Process	GO:0006930	substrate-dependent cell migration, cell extension	IGI	J:149136
Biological Process	GO:0006930	substrate-dependent cell migration, cell extension	IGI	J:149136
Biological Process	GO:0060074	synapse maturation	IDA	J:234334
Biological Process	GO:0060074	synapse maturation	IDA	J:234334
Biological Process	GO:0060074	synapse maturation	IMP	J:234334
Biological Process	GO:0008542	visual learning	IGI	J:182501

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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