GO Annotations Graph

• Symbol: Ache
• Name: acetylcholinesterase
• ID: MGI:87876

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042166	acetylcholine binding	ISO	J:155856
Molecular Function	GO:0042166	acetylcholine binding	ISO	J:164563
Molecular Function	GO:0003990	acetylcholinesterase activity	ISO	J:164563
Molecular Function	GO:0003990	acetylcholinesterase activity	ISO	J:155856
Molecular Function	GO:0003990	acetylcholinesterase activity	IBA	J:265628
Molecular Function	GO:0003990	acetylcholinesterase activity	IDA	J:17788
Molecular Function	GO:0003990	acetylcholinesterase activity	IDA	J:111571
Molecular Function	GO:0052689	carboxylic ester hydrolase activity	IEA	J:60000
Molecular Function	GO:0033265	choline binding	ISO	J:155856
Molecular Function	GO:0004104	cholinesterase activity	ISO	J:164563
Molecular Function	GO:0005518	collagen binding	ISO	J:164563
Molecular Function	GO:0016787	hydrolase activity	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:31461
Molecular Function	GO:0043236	laminin binding	ISO	J:164563
Molecular Function	GO:0043236	laminin binding	IPI	J:93292
Molecular Function	GO:0005515	protein binding	IPI	J:157644
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0043621	protein self-association	IPI	J:31461
Molecular Function	GO:0017171	serine hydrolase activity	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0005604	basement membrane	IDA	J:23783
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:111571
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005788	endoplasmic reticulum lumen	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:111571
Cellular Component	GO:0005615	extracellular space	IDA	J:31461
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0031594	neuromuscular junction	ISO	J:155856
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:23783
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005635	nuclear envelope	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:31461
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	ISO	J:155856
Cellular Component	GO:0005791	rough endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:155856
Cellular Component	GO:0045202	synapse	ISO	J:164563
Cellular Component	GO:0045202	synapse	IDA	J:81738
Cellular Component	GO:0045202	synapse	IDA	J:76455
Cellular Component	GO:0043083	synaptic cleft	ISO	J:155856
Cellular Component	GO:0043083	synaptic cleft	ISO	J:155856
Biological Process	GO:0006581	acetylcholine catabolic process	ISO	J:164563
Biological Process	GO:0006581	acetylcholine catabolic process	ISO	J:155856
Biological Process	GO:0006581	acetylcholine catabolic process	IBA	J:265628
Biological Process	GO:0006581	acetylcholine catabolic process	IDA	J:111571
Biological Process	GO:0006581	acetylcholine catabolic process	IDA	J:17788
Biological Process	GO:0008291	acetylcholine metabolic process	ISO	J:155856
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	IMP	J:103439
Biological Process	GO:0007155	cell adhesion	ISO	J:164563
Biological Process	GO:0019695	choline metabolic process	ISO	J:155856
Biological Process	GO:0019695	choline metabolic process	IBA	J:265628
Biological Process	GO:0070997	neuron death	ISO	J:155856
Biological Process	GO:0042135	neurotransmitter catabolic process	IEA	J:60000
Biological Process	GO:0050772	positive regulation of axonogenesis	ISO	J:155856
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:140622
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0031623	receptor internalization	IMP	J:103439
Biological Process	GO:0001919	regulation of receptor recycling	IMP	J:103439
Biological Process	GO:0046677	response to antibiotic	ISO	J:155856
Biological Process	GO:0032868	response to insulin	ISO	J:155856
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:101277
Biological Process	GO:0007416	synapse assembly	ISO	J:155856