GO Annotations Graph

• Symbol: Aco2
• Name: aconitase 2, mitochondrial
• ID: MGI:87880

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051538	3 iron, 4 sulfur cluster binding	ISO	J:155856
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	ISO	J:155856
Molecular Function	GO:0051539	4 iron, 4 sulfur cluster binding	IBA	J:265628
Molecular Function	GO:0003994	aconitate hydratase activity	ISO	J:164563
Molecular Function	GO:0003994	aconitate hydratase activity	ISO	J:155856
Molecular Function	GO:0003994	aconitate hydratase activity	IBA	J:265628
Molecular Function	GO:0003994	aconitate hydratase activity	IDA	J:330208
Molecular Function	GO:0003994	aconitate hydratase activity	IDA	J:94963
Molecular Function	GO:0003994	aconitate hydratase activity	IDA	J:94963
Molecular Function	GO:0003994	aconitate hydratase activity	IDA	J:121138
Molecular Function	GO:0047780	citrate dehydratase activity	IEA	J:72245
Molecular Function	GO:0005506	iron ion binding	ISO	J:73065
Molecular Function	GO:0051536	iron-sulfur cluster binding	IEA	J:60000
Molecular Function	GO:0016829	lyase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005759	mitochondrial matrix	IDA	J:330208
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:121138
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Biological Process	GO:0006101	citrate metabolic process	ISO	J:155856
Biological Process	GO:0006101	citrate metabolic process	ISO	J:73065
Biological Process	GO:0006102	isocitrate metabolic process	ISO	J:155856
Biological Process	GO:0006099	tricarboxylic acid cycle	ISO	J:155856
Biological Process	GO:0006099	tricarboxylic acid cycle	IBA	J:265628
Biological Process	GO:0006099	tricarboxylic acid cycle	IGI	J:330208
Biological Process	GO:0006099	tricarboxylic acid cycle	ISO	J:73065