GO Annotations Graph

• Symbol: Acr
• Name: acrosin prepropeptide
• ID: MGI:87884

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0005537	mannose binding	ISO	J:164563
Molecular Function	GO:0008233	peptidase activity	IMP	J:38658
Molecular Function	GO:0008233	peptidase activity	IMP	J:21944
Molecular Function	GO:0005515	protein binding	IPI	J:73170
Molecular Function	GO:0005515	protein binding	IPI	J:73170
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0004252	serine-type endopeptidase activity	TAS	J:113961
Molecular Function	GO:0004252	serine-type endopeptidase activity	IBA	J:265628
Molecular Function	GO:0008236	serine-type peptidase activity	IEA	J:60000
Cellular Component	GO:0043159	acrosomal matrix	TAS	J:113961
Cellular Component	GO:0001669	acrosomal vesicle	ISO	J:155856
Cellular Component	GO:0001669	acrosomal vesicle	IDA	J:21948
Cellular Component	GO:0005798	Golgi-associated vesicle	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Biological Process	GO:0002077	acrosome matrix dispersal	ISO	J:155856
Biological Process	GO:0007340	acrosome reaction	TAS	J:113961
Biological Process	GO:0007340	acrosome reaction	ISO	J:164563
Biological Process	GO:0007340	acrosome reaction	IBA	J:265628
Biological Process	GO:0007190	activation of adenylate cyclase activity	ISO	J:164563
Biological Process	GO:0007339	binding of sperm to zona pellucida	IGI	J:98301
Biological Process	GO:0007339	binding of sperm to zona pellucida	IGI	J:98301
Biological Process	GO:0007339	binding of sperm to zona pellucida	IGI	J:98301
Biological Process	GO:0007341	penetration of zona pellucida	ISO	J:155856
Biological Process	GO:0007341	penetration of zona pellucida	IGI	J:90008
Biological Process	GO:0007341	penetration of zona pellucida	IMP	J:21944
Biological Process	GO:0007341	penetration of zona pellucida	IMP	J:38658
Biological Process	GO:0030163	protein catabolic process	ISO	J:155856
Biological Process	GO:0006508	proteolysis	IEA	J:72247
Biological Process	GO:0006508	proteolysis	IEA	J:60000
Biological Process	GO:0048545	response to steroid hormone	ISO	J:155856
Biological Process	GO:0007338	single fertilization	IMP	J:98301