GO Annotations Graph

• Symbol: Actb
• Name: actin, beta
• ID: MGI:87904

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0019894	kinesin binding	ISO	J:164563
Molecular Function	GO:0050998	nitric-oxide synthase binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:105078
Molecular Function	GO:0005515	protein binding	IPI	J:122748
Molecular Function	GO:0005515	protein binding	IPI	J:222132
Molecular Function	GO:0005515	protein binding	IPI	J:144029
Molecular Function	GO:0005515	protein binding	IPI	J:233627
Molecular Function	GO:0005515	protein binding	IPI	J:261913
Molecular Function	GO:0005515	protein binding	IPI	J:177167
Molecular Function	GO:0005515	protein binding	IPI	J:165948
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0098973	structural constituent of postsynaptic actin cytoskeleton	ISO	J:164563
Molecular Function	GO:0030957	Tat protein binding	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0043296	apical junction complex	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0140092	bBAF complex	NAS	J:156242
Cellular Component	GO:0035060	brahma complex	NAS	J:35263
Cellular Component	GO:0005903	brush border	IDA	J:300338
Cellular Component	GO:0044305	calyx of Held	IDA	J:263458
Cellular Component	GO:0044305	calyx of Held	IDA	J:263458
Cellular Component	GO:0044305	calyx of Held	IDA	J:263458
Cellular Component	GO:0044305	calyx of Held	IMP	J:263458
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0000785	chromatin	NAS	J:283189
Cellular Component	GO:0000785	chromatin	NAS	J:320042
Cellular Component	GO:0030863	cortical cytoskeleton	IDA	J:138919
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:252003
Cellular Component	GO:0005737	cytoplasm	IDA	J:255730
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	ISO	J:155856
Cellular Component	GO:0005856	cytoskeleton	IDA	J:252003
Cellular Component	GO:0005856	cytoskeleton	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2316348
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2316351
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0005829	cytosol	IDA	J:75807
Cellular Component	GO:0005829	cytosol	IDA	J:93333
Cellular Component	GO:0140288	GBAF complex	NAS	J:283189
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	NAS	J:320056
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0071565	nBAF complex	NAS	J:132101
Cellular Component	GO:0071564	npBAF complex	NAS	J:35263
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	ISO	J:164563
Cellular Component	GO:0016363	nuclear matrix	NAS	J:320261
Cellular Component	GO:0000786	nucleosome	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:255730
Cellular Component	GO:0002102	podosome	ISO	J:155856
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:164563
Cellular Component	GO:0016586	RSC-type complex	NAS	J:35263
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263458
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:263458
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263458
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263458
Cellular Component	GO:0001725	stress fiber	ISO	J:155856
Cellular Component	GO:0016514	SWI/SNF complex	NAS	J:35263
Cellular Component	GO:0070160	tight junction	ISO	J:164563
Biological Process	GO:0034333	adherens junction assembly	ISO	J:164563
Biological Process	GO:0045176	apical protein localization	ISO	J:164563
Biological Process	GO:0007409	axonogenesis	ISO	J:155856
Biological Process	GO:0048870	cell motility	ISO	J:164563
Biological Process	GO:0072749	cellular response to cytochalasin B	ISO	J:164563
Biological Process	GO:0071257	cellular response to electrical stimulus	ISO	J:155856
Biological Process	GO:0006338	chromatin remodeling	NAS	J:283189
Biological Process	GO:0006338	chromatin remodeling	NAS	J:320039
Biological Process	GO:0007163	establishment or maintenance of cell polarity	ISO	J:164563
Biological Process	GO:0016573	histone acetylation	NAS	J:320265
Biological Process	GO:0043968	histone H2A acetylation	ISO	J:164563
Biological Process	GO:0043967	histone H4 acetylation	ISO	J:164563
Biological Process	GO:0001738	morphogenesis of a polarized epithelium	ISO	J:164563
Biological Process	GO:0045596	negative regulation of cell differentiation	NAS	J:268334
Biological Process	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	IC	J:144029
Biological Process	GO:0032091	negative regulation of protein binding	IDA	J:144029
Biological Process	GO:0045597	positive regulation of cell differentiation	NAS	J:156242
Biological Process	GO:0045597	positive regulation of cell differentiation	NAS	J:74389
Biological Process	GO:0008284	positive regulation of cell population proliferation	NAS	J:283189
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NAS	J:319957
Biological Process	GO:2000781	positive regulation of double-strand break repair	NAS	J:319964
Biological Process	GO:2000781	positive regulation of double-strand break repair	NAS	J:319983
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:0045663	positive regulation of myoblast differentiation	NAS	J:319991
Biological Process	GO:0045663	positive regulation of myoblast differentiation	NAS	J:320040
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	NAS	J:268334
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	NAS	J:147141
Biological Process	GO:0045582	positive regulation of T cell differentiation	NAS	J:131676
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	ISO	J:164563
Biological Process	GO:0071896	protein localization to adherens junction	ISO	J:164563
Biological Process	GO:0042981	regulation of apoptotic process	NAS	J:320265
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:155856
Biological Process	GO:2000779	regulation of double-strand break repair	NAS	J:320265
Biological Process	GO:0070316	regulation of G0 to G1 transition	NAS	J:74389
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	NAS	J:320113
Biological Process	GO:0030071	regulation of mitotic metaphase/anaphase transition	NAS	J:319964
Biological Process	GO:0030071	regulation of mitotic metaphase/anaphase transition	NAS	J:198738
Biological Process	GO:0051621	regulation of norepinephrine uptake	ISO	J:164563
Biological Process	GO:0051621	regulation of norepinephrine uptake	ISO	J:155856
Biological Process	GO:2000819	regulation of nucleotide-excision repair	NAS	J:320041
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:320308
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:132101
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:68501
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:320112
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	NAS	J:283189
Biological Process	GO:0150111	regulation of transepithelial transport	ISO	J:164563
Biological Process	GO:0022898	regulation of transmembrane transporter activity	ISO	J:164563
Biological Process	GO:0022898	regulation of transmembrane transporter activity	ISO	J:155856