GO Annotations Graph

• Symbol: Actg1
• Name: actin, gamma, cytoplasmic 1
• ID: MGI:87906

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005522	profilin binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:150861
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Molecular Function	GO:0005200	structural constituent of cytoskeleton	IDA	J:92541
Molecular Function	GO:0098973	structural constituent of postsynaptic actin cytoskeleton	ISO	J:155856
Molecular Function	GO:0098973	structural constituent of postsynaptic actin cytoskeleton	ISO	J:155856
Molecular Function	GO:0098973	structural constituent of postsynaptic actin cytoskeleton	IBA	J:265628
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:267879
Cellular Component	GO:0015629	actin cytoskeleton	IDA	J:92541
Cellular Component	GO:0005884	actin filament	ISO	J:164563
Cellular Component	GO:0043296	apical junction complex	ISO	J:164563
Cellular Component	GO:0045177	apical part of cell	IDA	J:267879
Cellular Component	GO:0120220	basal body patch	IDA	J:267879
Cellular Component	GO:0044305	calyx of Held	IDA	J:263458
Cellular Component	GO:0044305	calyx of Held	IDA	J:263458
Cellular Component	GO:0044305	calyx of Held	IMP	J:263458
Cellular Component	GO:0044305	calyx of Held	IDA	J:263458
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0043034	costamere	TAS	J:92541
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2316348
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-2316351
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0031941	filamentous actin	IDA	J:142574
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0030016	myofibril	IDA	J:92541
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	IBA	J:265628
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:143718
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	ISO	J:155856
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	ISO	J:155856
Cellular Component	GO:0099143	presynaptic actin cytoskeleton	ISO	J:155856
Cellular Component	GO:0099143	presynaptic actin cytoskeleton	ISO	J:155856
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263458
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IMP	J:263458
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263458
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	IDA	J:263458
Cellular Component	GO:0045202	synapse	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0048870	cell motility	IBA	J:265628
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:143718
Biological Process	GO:0001738	morphogenesis of a polarized epithelium	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0090303	positive regulation of wound healing	ISO	J:164563
Biological Process	GO:1902396	protein localization to bicellular tight junction	ISO	J:164563
Biological Process	GO:0051893	regulation of focal adhesion assembly	ISO	J:164563
Biological Process	GO:0051492	regulation of stress fiber assembly	ISO	J:164563
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IDA	J:263458
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	IMP	J:263458
Biological Process	GO:0150111	regulation of transepithelial transport	ISO	J:164563
Biological Process	GO:0045214	sarcomere organization	IDA	J:92541
Biological Process	GO:0120192	tight junction assembly	ISO	J:164563