GO Annotations Graph

• Symbol: Add1
• Name: adducin 1
• ID: MGI:87918

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IEA	J:60000
Molecular Function	GO:0051015	actin filament binding	ISO	J:164563
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0030507	spectrin binding	ISO	J:164563
Molecular Function	GO:0005200	structural constituent of cytoskeleton	IDA	J:71029
Molecular Function	GO:0042608	T cell receptor binding	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	IMP	J:235423
Cellular Component	GO:0005912	adherens junction	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005856	cytoskeleton	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IDA	J:71029
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0043197	dendritic spine	ISO	J:155856
Cellular Component	GO:0008290	F-actin capping protein complex	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:71029
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IMP	J:235423
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	IBA	J:265628
Cellular Component	GO:0045202	synapse	ISO	J:155856
Biological Process	GO:0051017	actin filament bundle assembly	ISO	J:164563
Biological Process	GO:0051016	barbed-end actin filament capping	ISO	J:164563
Biological Process	GO:0051016	barbed-end actin filament capping	IBA	J:265628
Biological Process	GO:0000902	cell morphogenesis	IMP	J:138919
Biological Process	GO:0006884	cell volume homeostasis	IMP	J:138919
Biological Process	GO:0071277	cellular response to calcium ion	IDA	J:235423
Biological Process	GO:0071277	cellular response to calcium ion	ISO	J:164563
Biological Process	GO:0071300	cellular response to retinoic acid	ISO	J:155856
Biological Process	GO:0030218	erythrocyte differentiation	IMP	J:138919
Biological Process	GO:0020027	hemoglobin metabolic process	IMP	J:138919
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	IMP	J:138919
Biological Process	GO:0001701	in utero embryonic development	IMP	J:138919
Biological Process	GO:0035264	multicellular organism growth	IMP	J:138919
Biological Process	GO:0030837	negative regulation of actin filament polymerization	ISO	J:155856
Biological Process	GO:1903393	positive regulation of adherens junction organization	ISO	J:164563
Biological Process	GO:1903393	positive regulation of adherens junction organization	IMP	J:235423
Biological Process	GO:1903393	positive regulation of adherens junction organization	IBA	J:265628
Biological Process	GO:0045766	positive regulation of angiogenesis	ISO	J:155856
Biological Process	GO:0045807	positive regulation of endocytosis	ISO	J:155856
Biological Process	GO:1903142	positive regulation of establishment of endothelial barrier	IMP	J:235423
Biological Process	GO:1903142	positive regulation of establishment of endothelial barrier	ISO	J:164563
Biological Process	GO:1903142	positive regulation of establishment of endothelial barrier	IBA	J:265628
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:164563